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腺瘤性癌的治疗。

Treatment of carcinoma in adenomas.

作者信息

Muto T, Sawada T, Sugihara K

机构信息

Department of Surgery, University of Tokyo, Japan.

出版信息

World J Surg. 1991 Jan-Feb;15(1):35-40. doi: 10.1007/BF01658958.

DOI:10.1007/BF01658958
PMID:1994604
Abstract

Invasive carcinomas in polyps removed during endoscopy are described. Most of them can be treated adequately by polypectomy alone, but some need additional surgical treatment. Incomplete excision, poorly-differentiated carcinoma, and lymphatic invasion are associated with increased risk of residual carcinoma and lymph node metastases, making colorectal resection more attractive; however, in elderly patients and poor-risk patients, the risks of surgery should be balanced against the possible advantage of curative surgery. Rectal polyps may be large but sphincter preservation can usually be achieved by different types of local excision. Recently described flat adenomas may contain carcinoma, but may also be treated by polypectomy using snare or hot biopsy.

摘要

本文描述了在内镜检查期间切除的息肉中的浸润性癌。其中大多数仅通过息肉切除术即可得到充分治疗,但有些则需要额外的手术治疗。切除不完全、低分化癌和淋巴浸润与残留癌和淋巴结转移风险增加相关,这使得结直肠切除术更具吸引力;然而,对于老年患者和高风险患者,手术风险应与根治性手术可能带来的益处相权衡。直肠息肉可能很大,但通常可以通过不同类型的局部切除术来保留括约肌。最近报道的扁平腺瘤可能含有癌,但也可以通过圈套器或热活检进行息肉切除术来治疗。

相似文献

1
Treatment of carcinoma in adenomas.腺瘤性癌的治疗。
World J Surg. 1991 Jan-Feb;15(1):35-40. doi: 10.1007/BF01658958.
2
[Colorectal polyps in a hospital of Metropolitan Lima].[利马都会区一家医院的大肠息肉]
Rev Gastroenterol Peru. 1995 Jan-Apr;15(1):21-5.
3
[Endoscopic polypectomy in benign adenoma and in early colo-rectal lesions].[内镜下切除良性腺瘤及早期结直肠病变]
G Chir. 1999 Oct;20(10):436-9.
4
Management of invasive carcinoma in pedunculated colorectal polyps.带蒂结直肠息肉浸润性癌的管理
Oncology (Williston Park). 1989 Jul;3(7):99-104; discussion 104-5.
5
Outcomes of EMR of defiant colorectal lesions directed to an endoscopy referral center.内镜转诊中心导向的挑战性结直肠病变内镜黏膜下剥离术的结果。
Gastrointest Endosc. 2012 Aug;76(2):255-63. doi: 10.1016/j.gie.2012.02.060. Epub 2012 May 31.
6
Lymph node metastases from carcinomas developing in pedunculated and semipedunculated colorectal adenomas.有蒂和半有蒂大肠腺瘤发生癌变时的淋巴结转移情况。
Aust N Z J Surg. 1981 Oct;51(5):429-33. doi: 10.1111/j.1445-2197.1981.tb05977.x.
7
Management of patients with invasive carcinoma removed by colonoscopic polypectomy.
Dis Colon Rectum. 1989 Oct;32(10):829-34. doi: 10.1007/BF02554549.
8
[Endoscopic Therapy of Early Colorectal Cancer (pT1) - A Prospective Study].[早期结直肠癌(pT1)的内镜治疗——一项前瞻性研究]
Z Gastroenterol. 2003 Aug;41(8):703-10. doi: 10.1055/s-2003-41213.
9
Large colorectal polyps: colonoscopy, pathology, and management.大型结直肠息肉:结肠镜检查、病理学及管理
Am J Gastroenterol. 1989 Aug;84(8):898-905.
10
Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy.腺瘤性结直肠癌的预后因素:对经内镜息肉切除术切除病变的意义。
Gastroenterology. 1985 Aug;89(2):328-36. doi: 10.1016/0016-5085(85)90333-6.

引用本文的文献

1
Association Between Chemotherapy and Survival in T1 Colon Cancer With Lymph Node Metastasis: A Propensity-Score Matched Analysis.T1期伴淋巴结转移结肠癌化疗与生存的关联:倾向评分匹配分析
Front Oncol. 2021 Jul 30;11:699400. doi: 10.3389/fonc.2021.699400. eCollection 2021.
2
Rectal cancer: An evidence-based update for primary care providers.直肠癌:基层医疗服务提供者基于证据的最新资讯
World J Gastroenterol. 2015 Jul 7;21(25):7659-71. doi: 10.3748/wjg.v21.i25.7659.
3
Management of the malignant polyp.恶性息肉的管理

本文引用的文献

1
Endoscopic polypectomy of the large bowel: management of cancer-bearing polyps.
Int Surg. 1981 Oct-Dec;66(4):311-4.
2
Endoscopic polypectomy: inadequate treatment for invasive colorectal carcinoma.内镜下息肉切除术:对浸润性结直肠癌治疗不足
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Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2.通过抗细胞角蛋白抗体CAM5.2检测发现,黏膜下结直肠癌最深浸润边缘的肿瘤芽生与淋巴结转移相关。
Br J Cancer. 2006 Jan 30;94(2):293-8. doi: 10.1038/sj.bjc.6602927.
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[Risk factors for lymphatic metastasis from pT1 colorectal adenocarcinoma].[pT1期结直肠癌淋巴结转移的危险因素]
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Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas.基质溶素(MMP-7)作为早期浸润性结直肠癌恶性潜能的重要决定因素。
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Risk factor assessment of endoscopically removed malignant colorectal polyps.经内镜切除的恶性大肠息肉的危险因素评估
Gut. 1998 Nov;43(5):669-74. doi: 10.1136/gut.43.5.669.
Malignant colon polyps--cure by colonoscopy or colectomy?
恶性结肠息肉——通过结肠镜检查还是结肠切除术治愈?
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6
Management of patients with polyps containing malignancy removed by colonoscopic polypectomy.经结肠镜息肉切除术切除的含恶性肿瘤息肉患者的管理。
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7
Surgical pathology of endoscopically removed malignant polyps of the colon and rectum.经内镜切除的结肠和直肠恶性息肉的外科病理学
Am J Surg Pathol. 1983 Oct;7(7):613-23. doi: 10.1097/00000478-198310000-00002.
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Rational management of malignant colon polyps based on long-term follow-up.基于长期随访的恶性结肠息肉合理管理
Surgery. 1984 Oct;96(4):815-22.
9
Small pedunculated tubular adenoma of the colon with carcinoma restricted to the head, invasion of lymphatics and widespread metastases. Case report and review of the literature.结肠小带蒂管状腺瘤伴癌,癌局限于头部,有淋巴管侵犯及广泛转移。病例报告及文献复习。
Virchows Arch A Pathol Anat Histopathol. 1983;402(1):83-9. doi: 10.1007/BF00695051.
10
Distribution of human colonic lymphatics in normal, hyperplastic, and adenomatous tissue. Its relationship to metastasis from small carcinomas in pedunculated adenomas, with two case reports.人结肠淋巴管在正常、增生及腺瘤组织中的分布。其与有蒂腺瘤中小癌转移的关系,并附两例报告。
Gastroenterology. 1973 Jan;64(1):51-66.