鼻腔鼻窦和鼻咽部的错构瘤、乳头瘤和腺癌。
Hamartomas, papillomas and adenocarcinomas of the sinonasal tract and nasopharynx.
机构信息
Department of Pathology, University Health Network, Ontario M5G 2C4, Canada.
出版信息
J Clin Pathol. 2009 Dec;62(12):1085-95. doi: 10.1136/jcp.2007.053702.
Lesions of the sinonasal tract are uncommon, with most of the specimens seen by surgical pathologists consisting primarily of fragments of inflamed sinonasal mucosa or inflammatory polyps from patients with chronic rhinosinusitis, and the occasional squamous cell carcinoma. Other lesions such as hamartomas, various types of Schneiderian papillomas and adenocarcinomas are seen only rarely by most histopathologists; therefore a biopsy or surgical resection specimen from a patient with one of these processes may represent a diagnostic challenge. The aim of this review is to present the pathological features of a group of infrequent epithelial surface and glandular lesions of the sinonasal tract which includes respiratory epithelial adenomatoid hamartoma, glandular (seromucinous) hamartoma, exophytic papilloma, inverted papilloma, cylindrical cell (oncocytic) papilloma, low-grade sinonasal adenocarcinoma and intestinal-type sinonasal adenocarcinoma.
鼻腔鼻窦部位的病变并不常见,大多数接受外科病理检查的标本主要由慢性鼻-鼻窦炎患者的炎症性鼻黏膜或炎性息肉碎片以及偶尔的鳞状细胞癌组成。其他病变,如错构瘤、各种类型的嗅神经鞘瘤和腺癌,大多数组织病理学家很少见到;因此,来自这些病变之一的患者的活检或手术切除标本可能具有诊断挑战性。本次综述的目的是介绍一组罕见的鼻腔鼻窦上皮表面和腺体病变的病理特征,包括呼吸上皮腺样错构瘤、腺体(黏液性)错构瘤、外生性乳头状瘤、内翻性乳头状瘤、柱状细胞(嗜酸性细胞)乳头状瘤、低级别鼻腔鼻窦腺癌和肠型鼻腔鼻窦腺癌。