Basiari Lentiona, Michali Maria, Komnos Ioannis, Tsirves Georgios, Tsoumani Victoria, Kastanioudakis Ioannis
Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital of Ioannina, Ioannina, Greece.
Case Rep Otolaryngol. 2023 Aug 12;2023:1923015. doi: 10.1155/2023/1923015. eCollection 2023.
Seromucinous hamartoma is a rare benign glandular proliferation arising from the respiratory epithelium of the sinonasal tract and nasopharynx. It was described for the first time in 1974 by Baillie and Batsakis. Since then, few cases have been reported in the literature with most of them occurring in the posterior nasal septum. We report the case of a 52-year-old woman that presented to our department with left periorbital edema, pain, and dacryorrhea due to seromucinous hamartoma arising from the left inferior turbinate and extending through the lateral nasal wall into the maxilla, the nasolacrimal duct, and the orbit. Endoscopic medial maxillectomy and endoscopic transnasal orbital tumor resection were performed. The patient remains symptom-free for 16 months, till her most recent follow-up. Seromucinous hamartoma of the nasal cavity is an exceedingly rare diagnosis, especially in the lateral nasal wall. It should be included in the differential diagnosis of nasal tumors. According to the literature review, this is the first case report of seromucinous hamartoma with orbit infiltration. Endonasal endoscopic resection is the treatment of choice.
浆液黏液性错构瘤是一种罕见的良性腺体增生，起源于鼻窦和鼻咽部的呼吸道上皮。1974年，贝利和巴塔基斯首次对其进行了描述。从那时起，文献中报道的病例很少，其中大多数发生在鼻中隔后部。我们报告了一例52岁女性患者，因左侧下鼻甲浆液黏液性错构瘤，经鼻外侧壁延伸至上颌骨、鼻泪管和眼眶，导致左侧眶周水肿、疼痛和溢泪，前来我院就诊。我们实施了内镜下上颌骨内侧切除术和内镜经鼻眼眶肿瘤切除术。直到最近一次随访，患者已16个月无症状。鼻腔浆液黏液性错构瘤的诊断极为罕见，尤其是在鼻外侧壁。它应列入鼻腔肿瘤的鉴别诊断。根据文献综述，这是第一例浆液黏液性错构瘤浸润眼眶的病例报告。鼻内镜下切除术是首选的治疗方法。
