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Case series of cetuximab monotherapy for patients with pre-treated colorectal cancer complicated with hyperbilirubinemia due to severe liver metastasis.

作者信息

Shitara Kohei, Takahari Daisuke, Yokota Tomoya, Shibata Takashi, Ura Takashi, Muro Kei, Inaba Yoshitaka, Yamaura Hidekazu, Sato Yozo, Najima Mina, Utsunomiya Setsuo

出版信息

Jpn J Clin Oncol. 2010 Mar;40(3):275-7. doi: 10.1093/jjco/hyp161. Epub 2009 Nov 28.

DOI:10.1093/jjco/hyp161
PMID:19946122
Abstract
摘要

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Case series of cetuximab monotherapy for patients with pre-treated colorectal cancer complicated with hyperbilirubinemia due to severe liver metastasis.
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[Two cases of colorectal cancer patients with poor performance status who had unresectable liver metastasis effectively treated by cetuximab].[两例体力状况差且伴有不可切除肝转移的结直肠癌患者经西妥昔单抗治疗有效]
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Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab.埃皮瑞利素、双调蛋白的表达及K-ras突变状态可预测接受西妥昔单抗治疗的转移性结直肠癌患者的疾病控制情况。
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The use cetuximab after oxaliplatin-based chemotherapy in a patient with metastatic colorectal cancer.在一名转移性结直肠癌患者中，在基于奥沙利铂的化疗后使用西妥昔单抗。
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Anti-EGFR antibody monotherapy for colorectal cancer with severe hyperbilirubinemia: A case report.抗表皮生长因子受体（EGFR）抗体单药治疗严重高胆红素血症的结直肠癌：一例报告
World J Gastrointest Oncol. 2024 Feb 15;16(2):557-562. doi: 10.4251/wjgo.v16.i2.557.
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Treatment approach in patients with hyperbilirubinemia secondary to liver metastases in gastrointestinal malignancies: a case series and review of literature.
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Chemotherapy in the Setting of Severe Liver Dysfunction in Patients with Metastatic Colorectal Cancer.转移性结直肠癌患者严重肝功能不全时的化疗
Case Rep Oncol Med. 2015;2015:420159. doi: 10.1155/2015/420159. Epub 2015 May 21.