Frank T S, Bhat N, Noumoff J S, Yeh I T
Department of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, Philadelphia.
Acta Cytol. 1991 Jan-Feb;35(1):105-8.
A cervicovaginal smear containing atypical cells, which were interpreted as dysplastic cells, was obtained from a women one-year postpartum. These cells were seen singly, in small groups and in clusters embedded in an amorphous pink matrix. They had amphophilic cytoplasm and increased nuclear/cytoplasmic ratios, as well as hyperchromatic nuclei with variably prominent nucleoli, features that are characteristic of trophoblastic cells. No evidence of dysplasia was seen on subsequent colposcopic examination or cervical biopsy. Endocervical curettage yielded fragments of exfoliated endometrium and residual trophoblastic tissue associated with a placental implantation site. Although involution of the placental site is generally complete by six to seven weeks postpartum, maternal-fetal tissue may in fact continue to be exfoliated for several months or longer after delivery. If seen on a cervicovaginal smear, these cells can be highly atypical and may be mistaken as dysplastic or malignant. The cytologic features that characterize trophoblasts and their persistence in postpartum cervicovaginal smears are discussed.
从一名产后一年的女性身上获取了一份宫颈阴道涂片，其中含有非典型细胞，这些细胞被解释为发育异常细胞。这些细胞单个出现，也成小群或簇状，嵌于无定形粉红色基质中。它们具有嗜双色性细胞质，核质比增加，核染色质增多，核仁大小不一且突出，这些都是滋养层细胞的特征。随后的阴道镜检查或宫颈活检未发现发育异常的证据。宫颈管搔刮术获取了脱落的子宫内膜碎片和与胎盘植入部位相关的残留滋养层组织。尽管胎盘部位的 involution 通常在产后六到七周完成，但母婴组织实际上可能在分娩后数月或更长时间内继续脱落。如果在宫颈阴道涂片中看到这些细胞，它们可能高度非典型，可能被误认为发育异常或恶性。本文讨论了滋养层细胞的细胞学特征及其在产后宫颈阴道涂片中的持续存在情况。 （注：原文中“involution”此处可能有误，根据语境推测可能是“退化”之类的意思，但由于原文如此，暂按原样翻译）
