Yang Isaac, Paik Elena, Huh Nancy G, Parsa Andrew T, Ames Christopher P
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
J Med Case Rep. 2009 Oct 30;3:88. doi: 10.1186/1752-1947-3-88.
Giant intradural extramedullary schwannomas of the thoracic spine are not common. Schwannomas, that is, tumors derived from neoplastic Schwann cells, and neurofibromas represent the most common intradural extramedullary spinal lesions. We report the case of a patient with a giant thoracic schwannoma presenting unusually with acute abdominal pain and with delayed neurological impairment.
A 26-year-old Hispanic man with no previous medical problems presented with acute periumbilical pain. After extensive work-up including an exploratory laparotomy for appendectomy, magnetic resonance imaging scans of the lumbar and thoracic spine revealed a giant intradural extramedullary thoracic schwannoma within the spinal canal posterior to the T9, T10, and T11 vertebral bodies. Magnetic resonance imaging signal prolongation was noted in the spinal cord both rostral and caudal to the schwannoma. The patient underwent an urgent laminectomy from T8 to L1. After sacrificing the T10 root, the tumor was removed en bloc. Postoperatively, the patient improved significantly gaining antigravity strength in both lower extremities.
The T10 dermatome is represented by the umbilical region. This referred pain may represent a mechanism by which a giant thoracic schwannoma may present as acute abdominal pain. Acute, intense abdominal pain with delayed neurologic deficit is a rare presentation of a thoracic schwannoma but should be considered as a possible cause of abdominal pain presenting without clear etiology. Although these lesions may be delayed in their diagnosis, early diagnosis and treatment may lead to an improved clinical outcome.
胸段脊柱巨大硬膜内髓外神经鞘瘤并不常见。神经鞘瘤,即源自肿瘤性施万细胞的肿瘤,以及神经纤维瘤是最常见的硬膜内髓外脊柱病变。我们报告一例胸段巨大神经鞘瘤患者,其表现为异常的急性腹痛和延迟性神经功能损害。
一名26岁的西班牙裔男性,既往无病史,因急性脐周疼痛就诊。经过包括剖腹探查阑尾切除术在内的广泛检查后,腰椎和胸椎的磁共振成像扫描显示,在T9、T10和T11椎体后方的椎管内有一个巨大的硬膜内髓外胸段神经鞘瘤。在神经鞘瘤头侧和尾侧的脊髓中均发现磁共振成像信号延长。患者接受了从T8到L1的紧急椎板切除术。在牺牲T10神经根后,将肿瘤整块切除。术后,患者明显好转,双下肢获得了抗重力力量。
脐周区域代表T10皮节。这种牵涉痛可能是巨大胸段神经鞘瘤表现为急性腹痛的一种机制。伴有延迟性神经功能缺损的急性、剧烈腹痛是胸段神经鞘瘤的一种罕见表现,但应被视为无明确病因的腹痛的可能原因。尽管这些病变的诊断可能会延迟,但早期诊断和治疗可能会改善临床结局。