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胸椎硬脊膜内血管外皮细胞瘤:1 例报告。

Intradural hemangiopericytoma of the thoracic spine: a case report.

机构信息

Department of Neurological Surgery, Loyola University Medical Center, Maywood, IL 60153, USA.

出版信息

Spine J. 2011 Jul;11(7):e9-e14. doi: 10.1016/j.spinee.2011.04.030. Epub 2011 Jun 8.

Abstract

BACKGROUND CONTEXT

Hemangiopericytoma (HPC) occurs infrequently in the central nervous system. Spinal involvement is particularly uncommon; and intradural localization is rare. Here, we describe an intradural extramedullary thoracic HPC that went undiagnosed initially on computed tomography scan of the abdomen.

PURPOSE

To describe the clinical presentation and operative management of a patient diagnosed with an intradural extramedullary thoracic HPC that was missed on initial workup. We also describe the pathologic features of HPC.

STUDY DESIGN

Case report.

METHODS

Chart review and literature search.

CASE

A 58-year-old man presented with acute weakness of the lower extremities and bladder and bowel incontinence. Magnetic resonance imaging of his spine revealed a T10 intradural extramedullary lesion that displaced the cord to the right.

RESULTS

The patient was taken emergently to surgery for T9-T11 laminectomy and en bloc resection of the tumor. The lesion was identified and resected. Histology revealed randomly oriented tumor cells with irregular capillaries consistent with HPC. Postoperatively, the patient had an improved neurological examination, and he continued to do so with intense physical therapy.

CONCLUSION

The standard treatment for HPC is surgery when the lesion is resectable. Despite gross total resection, there is still a high risk of recurrence and metastasis; therefore, patients should be followed up closely by their physicians with serial postoperative clinical examinations and radiographic imaging.

摘要

背景

中枢神经系统中血管外皮细胞瘤(HPC)的发生率较低。椎管内受累尤其罕见;硬脊膜内定位则更为罕见。在此,我们描述了一例最初在腹部计算机断层扫描(CT)上未被诊断的胸段硬脊膜外 HPC。

目的

描述一例最初未被诊断的胸段硬脊膜外 HPC 患者的临床表现和手术治疗。我们还描述了 HPC 的病理特征。

设计

病例报告。

方法

病历回顾和文献检索。

病例

一名 58 岁男性因下肢无力、膀胱和肠道失禁就诊。脊柱磁共振成像显示 T10 硬脊膜外髓内病变,脊髓向右侧移位。

结果

患者紧急接受 T9-T11 椎板切除术和肿瘤整块切除术。肿瘤被识别并切除。组织学显示肿瘤细胞呈不规则排列,伴不规则毛细血管,符合 HPC。术后,患者的神经功能检查得到改善,并继续接受强化物理治疗。

结论

当病变可切除时,HPC 的标准治疗方法是手术。尽管实现了大体全切除,但仍有很高的复发和转移风险;因此,患者应在术后由医生通过定期临床检查和影像学检查进行密切随访。

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