van Weert Henk C P M, Pingen Francien
Academic Medical Centre Amsterdam, Dpt General Practice Meibergdreef 15, 1105 AZ Amsterdam, the Netherlands.
Cases J. 2009 Oct 13;2:153. doi: 10.1186/1757-1626-2-153.
The association between unprovoked deep venous thrombosis or pulmonary embolism and malignancy is well established. For unprovoked superficial thrombophlebitis this association has been documented in a few case-reports only.
A 54-year-old apparently healthy male presents for the fourth time with an unprovoked superficial thrombophlebitis of the leg. When screened for underlying causes a renal cell carcinoma and an adenocarcinoma of the prostate are diagnosed. The renal cell carcinoma pointed out to have been visible on a CT-scan, made just before the time of the first presentation of the thrombophlebitis.
Unprovoked and recurrent thrombophlebitis is a rare condition and its presentation might be a warning sign for a (yet undiagnosed) cancer. Physicians should be on their guard and consider screening for cancer. Usefulness of such a screening however is not known.
不明原因的深静脉血栓形成或肺栓塞与恶性肿瘤之间的关联已得到充分证实。对于不明原因的浅静脉炎,这种关联仅在少数病例报告中有记载。
一名54岁看似健康的男性第四次出现不明原因的腿部浅静脉炎。在筛查潜在病因时,诊断出肾细胞癌和前列腺腺癌。肾细胞癌在首次出现浅静脉炎之前进行的CT扫描中就已可见。
不明原因的复发性静脉炎是一种罕见病症,其表现可能是(尚未诊断出的)癌症的警示信号。医生应保持警惕并考虑进行癌症筛查。然而,这种筛查的有效性尚不清楚。