宫腔镜检查中子宫内膜细胞播散风险的评估：一项前瞻性纵向研究。
Evaluation of the risk of spreading endometrial cell by hysteroscopy: a prospective longitudinal study.
作者信息
de Sousa Damião Rievani, Lopes Reginaldo Guedes Coelho, Dos Santos Emilly Serapião, Lippi Umberto Gazzi, da Fonseca Eduardo Borges
机构信息
Departamento de Obstetrícia e Ginecologia, Hospital do Servidor Publico Estadual, "Francisco Morato de Oliveira", Rua Pedro de Toledo 1800, 04039-901 São Paulo, SP, Brazil.
出版信息
Obstet Gynecol Int. 2009;2009:397079. doi: 10.1155/2009/397079. Epub 2009 May 25.
Objective. The aim was to assess the intraperitoneal spread of endometrial cells during hysteroscopy. Study Design. Seventy-six women were submitted to a hysteroscopy with CO(2) under a low pressure. Group 1 had not previous diagnosis of endometrial cancer, and group 2 had previous diagnosis of endometrial cancer (stage I-92.3%). Two peritoneal washing samples were taken before (PW1) and immediately after (PW2) the procedure. The dissemination for the peritoneal cavity was defined by the presence of endometrial cells in the PW2; such cells should be absent in WP1. Results. Four patients were excluded for presenting endometrial cells in PW1. In the 72 patients left, there was no passage of cells for the peritoneal cavity. In group 1, 88% presented secretory endometrial phase with correlation of 80% between hysteroscopy and biopsy. Conclusion. Hysteroscopy performed under a low pressure of CO(2) does not cause spreading of endometrial cells into the peritoneal cavity.
目的。本研究旨在评估宫腔镜检查期间子宫内膜细胞的腹腔内播散情况。研究设计。76名女性接受了低压二氧化碳宫腔镜检查。第1组既往无子宫内膜癌诊断，第2组既往有子宫内膜癌诊断（Ⅰ期占92.3%）。在手术前（PW1）和手术后立即（PW2）采集两份腹腔冲洗样本。腹腔播散通过PW2中存在子宫内膜细胞来定义；此类细胞在WP1中应不存在。结果。4例患者因PW1中出现子宫内膜细胞而被排除。在剩余的72例患者中，没有细胞进入腹腔。在第1组中，88%表现为分泌期子宫内膜，宫腔镜检查与活检的相关性为80%。结论。在低压二氧化碳条件下进行的宫腔镜检查不会导致子宫内膜细胞扩散到腹腔。
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