Watts Amy K, Thikkurissy S, Smiley Megann, McTigue Dennis J, Smith Tharon
The Ohio State University College of Dentistry, Nationwide Children's Hospital, Columbus, Ohio, USA.
Pediatr Dent. 2009 Sep-Oct;31(5):414-9.
The purpose of this study was to evaluate the use of intraoperative local anesthetics in pediatric outpatient dental surgery. This study assessed physiologic stability, as defined by fluctuations in end-tidol carbon dioxide, heart rate, and respiratory rate, as well as subsequent anesthesiologist intervention.
Forty-eight children (mean age = 3.87 years [+/- l.06 SD]) were included in this randomized, parallel-design study. Intervention variables and the research design were validated in a pilot study. Following collection of baseline vital signs, patients were either given local anesthesia before comprehensive dental treatment or not. Vital sign change was recorded 30 seconds after each procedure.
In the no local anesthetic group, 2 areas were found to be statistically significant: (1) postextraction end-tidal carbon dioxide; and (2) heart rate. There was a statistically significant relationship between local anesthetic use and anesthesiologist intervention when assessing the pooled data (P = .001).
Patients who were not given intraoperative local anesthesia were more likely to experience vital sign fluctuation requiring anesthesiologist intervention.
本研究旨在评估小儿门诊牙科手术中局部麻醉剂的使用情况。本研究评估了生理稳定性，其定义为呼气末二氧化碳、心率和呼吸频率的波动情况，以及随后麻醉医生的干预情况。
本随机平行设计研究纳入了48名儿童（平均年龄=3.87岁[±1.06标准差]）。干预变量和研究设计在一项初步研究中得到验证。在收集基线生命体征后，患者在接受全面牙科治疗前接受局部麻醉或不接受局部麻醉。每次手术后30秒记录生命体征变化。
在未使用局部麻醉剂的组中，发现有2个方面具有统计学意义：（1）拔牙后呼气末二氧化碳；（2）心率。在评估汇总数据时，局部麻醉剂的使用与麻醉医生的干预之间存在统计学上的显著关系（P = 0.001）。
未接受术中局部麻醉的患者更有可能出现需要麻醉医生干预的生命体征波动。
