Gremigni Paola, Sciarroni Laura, Pedrini Luciano
Department of Psychology, University of Bologna, Italy.
Monaldi Arch Chest Dis. 2009 Jun;72(2):91-7. doi: 10.4081/monaldi.2009.334.
The aim of this study was to investigate changes in cognitive function following carotid endarterectomy (CEA). In 74 asymptomatic CEA patients cognitive function, depression, laterality and severity of stenosis, cerebral Computer Tomography results, and ischemic heart diseases were measured preoperatively. The sample included 31 patients with dementia and 43 patients without any symptom of dementia. Cognitive function was measured again at 3 months postoperatively using a brief standardised test. After controlling for cognitive function and depression at baseline, cognitive function improved significantly at 3 months after CEA in both patients with and without dementia. CEA may offer more than reduced stroke risk to patients, independent of cognitive function.
本研究的目的是调查颈动脉内膜切除术(CEA)后认知功能的变化。对74例无症状CEA患者术前测量了认知功能、抑郁、狭窄的侧别和严重程度、脑计算机断层扫描结果以及缺血性心脏病情况。样本包括31例痴呆患者和43例无任何痴呆症状的患者。术后3个月使用简短标准化测试再次测量认知功能。在控制了基线时的认知功能和抑郁情况后,痴呆患者和非痴呆患者在CEA术后3个月时认知功能均有显著改善。CEA可能为患者带来除降低中风风险之外更多的益处,且与认知功能无关。