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[一氧化氮在生物体昼夜活动及抵御宇宙射线中的进化作用]

[The evolutionary role of nitric oxide in circadian activity and defense of the organism from cosmic rays].

作者信息

Iamshanov V A

出版信息

Adv Gerontol. 2009;22(2):282-4.

PMID:19947391
Abstract

The cosmic rays are one of the constantly acting factors influencing on genetic apparatus and depending from sun activity, which have the circadian rhythm. The nature creates a number of mechanisms, which defend the organism from cosmic rays and free radicals as consequence. However, the malfunctions of these mechanisms damage the genetic apparatus, accelerate the aging and bring to a number of illnesses. It is supposed that to neutralise the free radicals as cosmic rays consequence the organism uses its own free radicals, which have the physiological functions, for example, the nitric oxide. To limit the nitric oxide production, the mechanism of melatonin formation is used, which has a circadian rhythm.

摘要

宇宙射线是影响遗传机制的持续作用因素之一,它依赖于太阳活动,具有昼夜节律。大自然创造了许多机制来保护生物体免受宇宙射线和由此产生的自由基的伤害。然而,这些机制的故障会损害遗传机制,加速衰老并引发多种疾病。据推测,为了中和作为宇宙射线产物的自由基,生物体利用自身具有生理功能的自由基,例如一氧化氮。为了限制一氧化氮的产生,生物体利用了具有昼夜节律的褪黑素形成机制。

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