Chalisova N I, Romanov O E, Morozova P Iu, Balykina N A, Lesniak V V, Sukhonos Iu A, Zhekalov A N
Adv Gerontol. 2009;22(2):351-5.
The horn extracts from the saiga of different age were used to investigate its effect on organotypic tissue culture of explants from the rat spleen. From 4 to 10 amino acids were detected in the different extract fractions. The horn extracts from the young saiga, at the effective concentration 1 ng/ml, showed stimulating effect in spleen tissue cultures as compared to the control explants. No effect of extracts from the old saiga was observed in tissue culture. Possibly, a stimulation of the cellular proliferation is due to the great amino acid content in saiga horn; however this phenomenon is decreased by the aging.
采用不同年龄赛加羚羊角提取物，研究其对大鼠脾脏外植体器官型组织培养的影响。在不同提取物组分中检测到4至10种氨基酸。与对照外植体相比，幼龄赛加羚羊角提取物在有效浓度1 ng/ml时对脾脏组织培养有刺激作用。老龄赛加羚羊角提取物在组织培养中未观察到作用。细胞增殖的刺激作用可能归因于赛加羚羊角中丰富的氨基酸含量；然而，这种现象会随着衰老而减弱。
