变应性受试者中真菌变应原特异性IgE抗体反应的聚类
Clustering of fungal allergen-specific IgE antibody responses in allergic subjects.
作者信息
Potter P C, Juritz J, Little F, McCaldin M, Dowdle E B
机构信息
Department of Clinical Science and Immunology, Allergy Clinic, University of Cape Town, South Africa.
出版信息
Ann Allergy. 1991 Feb;66(2):149-53.
PMID:1994786
Abstract
Statistical analysis of specific IgE immune responses to a panel of nine allergens from 2,094 patients demonstrated significant clustering between Aspergillus fumigatus, Alternaria alternata, and Cladosporium herbarum, not explained by crossreactive elements. This may represent a linked, high responder status to these fungal antigens in the allergic population.
摘要
对来自2094名患者的针对一组9种过敏原的特异性IgE免疫反应进行的统计分析表明，烟曲霉、链格孢和枝孢之间存在显著聚类，这并非由交叉反应成分所解释。这可能代表了过敏人群中对这些真菌抗原的一种关联的高反应状态。
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