Topkara Veli K, Kondareddy Srikanth, Mann Douglas L
Cardiovascular Division, Washington University School of Medicine, 660 South Euclid Avenue, Campus PO Box 8066, Saint Louis, MO 63110, USA.
Curr Heart Fail Rep. 2009 Dec;6(4):229-35. doi: 10.1007/s11897-009-0032-6.
Myocardial infarction initiates progressive changes in the biology of the myocyte and nonmyocyte components of the myocardium, as well as the geometry of the left ventricle. Despite the use of evidence-based strategies to postmyocardial infarction, heart failure supervenes and is attended by an unacceptably high mortality rate. Given that left ventricular (LV) remodeling may contribute independently to disease progression, several innovative approaches have been designed to attenuate and reverse LV remodeling. This review discusses the emerging role of epicardial restraint devices in the treatment of postmyocardial cardiac remodeling.
心肌梗死会引发心肌中肌细胞和非肌细胞成分生物学特性的渐进性变化，以及左心室几何形状的改变。尽管在心肌梗死后采用了循证策略，但心力衰竭仍会接踵而至，且死亡率高得令人难以接受。鉴于左心室（LV）重构可能独立地促使疾病进展，人们设计了几种创新方法来减轻和逆转LV重构。本综述讨论了心外膜约束装置在心肌梗死后心脏重构治疗中的新作用。
