Adamson Philip B
Heart Failure Institute at Oklahoma Heart Hospital and Oklahoma Foundation for Cardiovascular Research, 4050 West Memorial Road, Oklahoma City, OK 73120, USA.
Curr Heart Fail Rep. 2009 Dec;6(4):287-92. doi: 10.1007/s11897-009-0039-z.
Studies of cardiovascular signals continuously sensed by implantable devices provide unique insight into detailed pathophysiology as patients progress from stable to congested states. These data suggest that volume expansion, autonomic adaptation, and pulmonary interstitial edema begin several weeks before patients develop symptoms or demonstrate changes in daily weight. Monitoring physiologic signals from implanted devices may provide earlier warning of impending decompensation, thereby allowing changes in medical therapy to prevent worsening heart failure.
对可植入设备持续感知的心血管信号进行的研究，为患者从稳定状态发展到充血状态时的详细病理生理学提供了独特的见解。这些数据表明，在患者出现症状或每日体重发生变化之前几周，容量扩张、自主神经适应和肺间质水肿就已开始。监测植入设备的生理信号可能会为即将发生的失代偿提供早期预警，从而使医疗治疗方案得以改变，以预防心力衰竭恶化。
