Department of Neurological, Neurosurgical and Behavioural Sciences, Clinical Neurophysiology Unit, University of Siena, Italy.
Clin Neurophysiol. 2010 Feb;121(2):208-13. doi: 10.1016/j.clinph.2009.09.031. Epub 2009 Nov 30.
To describe morphologic and functional modifications of the ulnar nerve at the wrist in carpal tunnel syndrome (CTS) after carpal tunnel release (CTR).
Ultrasonography was used to study the cross sectional area (CSA) of the ulnar nerve at Guyon's canal, before and 1 and 6 months after CTR, in 18 CTS patients. A parallel electrophysiological and clinical analysis was also conducted.
CSA of the ulnar nerve significantly increased 6 months after CTR. Ten (55%) cases showed abnormal CSA values compared to a control group before surgery and five (28%) at 6 month follow-up. In addition, there were improvements in the motor and sensory ulnar axon recruitment properties and the conduction values in sensory ulnar fibres. Patients with extra-median distribution of paresthesia (4 subjects) were free from symptoms.
CTR has a significant effect not only on the anatomical geometry of Guyon's canal, but also on the morphology and function of the ulnar nerve.
In CTS, high pressure in the carpal tunnel may result in anatomical changes of ulnar nerve, thus causing functional impairment to the ulnar fibres. CTR appears to reverse some of this damage.
描述正中神经在腕管松解术后(CTR)腕管综合征(CTS)时的形态和功能改变。
使用超声检查 18 例 CTS 患者腕管内 Guyon 管处尺神经的横截面积(CSA),分别在 CTR 前、1 个月和 6 个月进行测量。同时进行平行的电生理和临床分析。
CTR 后 6 个月尺神经 CSA 显著增加。与术前对照组相比,10 例(55%)出现异常 CSA 值,5 例(28%)在 6 个月随访时出现异常。此外,尺神经运动和感觉纤维的募集特性以及感觉纤维的传导值也有所改善。感觉异常分布于尺神经以外(4 例)的患者症状消失。
CTR 不仅对 Guyon 管的解剖几何形状有显著影响,而且对尺神经的形态和功能也有影响。
在 CTS 中,腕管内高压可能导致尺神经的解剖变化,从而导致尺神经纤维功能受损。CTR 似乎可以逆转部分这种损伤。