Zhang J, Liu N, Wang Y W, Zhang Z C, Zheng L N, Zhu J
Tianjin Medical University, Tianjin, China.
Department of Neurology, The Third Central Hospital of Tianjin, Tianjin, China.
Genet Mol Res. 2015 Apr 17;14(2):3680-6. doi: 10.4238/2015.April.17.17.
Many carpal tunnel syndrome (CTS) patients have symptoms in both the median and ulnar digits more frequently than in the median digits alone. This is possibly because of close anatomical contiguity of the carpal tunnel and Guyon's canal, and the high pressure may also affect the latter, causing indirect compression of ulnar nerve fibers. Thus, we evaluated the functional status of the ulnar nerve in patients with CTS in order to investigate the relationship between ulnar nerve impairment and sensory symptoms of the ulnar territory. Electrophysiological studies were conducted in CTS patients and healthy controls. CTS patients were divided into the mild/moderate group and severe group; they were further divided into the symptomatic and asymptomatic subgroups according to the sensory symptom of the fifth digit region. The findings suggest that CTS patients could have coexisting ulnar nerve wrist entrapments that might exacerbate the severity of CTS. Sensory impairment in the ulnar territory was observed more frequently in the mild/moderate stage of CTS, which is associated with ulnar nerve involvement. These findings also suggest that damage to the ulnar nerve fibers caused by compression forces in Guyon's canal may underlie the ulnar spread of symptoms in CTS.
许多腕管综合征(CTS)患者在正中指和尺侧指均出现症状的情况比仅在正中指出现症状更为常见。这可能是由于腕管和Guyon管在解剖结构上紧密相邻,高压也可能影响后者,导致尺神经纤维受到间接压迫。因此,我们评估了CTS患者尺神经的功能状态,以研究尺神经损伤与尺侧区域感觉症状之间的关系。对CTS患者和健康对照者进行了电生理研究。CTS患者被分为轻/中度组和重度组;根据小指区域的感觉症状,他们又进一步分为有症状亚组和无症状亚组。研究结果表明,CTS患者可能同时存在尺神经腕部卡压,这可能会加重CTS的严重程度。在CTS的轻/中度阶段,尺侧区域的感觉障碍更为常见,这与尺神经受累有关。这些发现还表明,Guyon管内的压迫力导致的尺神经纤维损伤可能是CTS症状向尺侧扩散的基础。