冠状动脉搭桥手术前后患者生活质量与性别差异的关系
Quality of life in patients related to gender differences before and after coronary artery bypass surgery.
作者信息
Peric Vladan, Borzanovic Milorad, Stolic Radojica, Jovanovic Aleksandar, Sovtic Sasa, Djikic Dijana, Marcetic Zoran, Dimkovic Sinisa
机构信息
Internal Clinic, School of Medicine, University of Pristina, Anri Didana bb, 38220 Kosovska Mitrovica, Serbia.
出版信息
Interact Cardiovasc Thorac Surg. 2010 Feb;10(2):232-8. doi: 10.1510/icvts.2009.208462. Epub 2009 Nov 30.
OBJECTIVES
The different aspects of quality of life (QOL) in patients of different sex structure have been examined as well as the presumption that sex structure could be a predictor of QOL changes after coronary artery bypass grafting (CABG).
METHODS
The study included 243 consecutive patients who underwent an elective CABG. The QOL analysis was performed by using structured interviews with the Nottingham Health Profile (NHP) questionnaire part 1.
RESULTS
Compared to men, women had worse preoperative QOL (in all sections except the section of sleep) and worse postoperative QOL (in all sections). Six months after CABG the QOL statistically improved in men and in women. Multivariate analysis showed that being female was an independent predictor of QOL worsening in section of pain [P=0.001, odds ratio (OR)=3.93, 95% confidence interval (CI) 1.74-8.88].
CONCLUSIONS
Compared to men, women have worse preoperative and postoperative QOL. Female sex was an independent predictor of QOL worsening six months after CABG.
目的
研究不同性别结构患者生活质量（QOL）的不同方面，并探讨性别结构是否可作为冠状动脉旁路移植术（CABG）后生活质量变化的预测指标。
方法
本研究纳入243例接受择期CABG的连续患者。采用诺丁汉健康量表（NHP）问卷第1部分进行结构化访谈，以分析生活质量。
结果
与男性相比，女性术前生活质量较差（除睡眠部分外的所有部分），术后生活质量也较差（所有部分）。CABG术后6个月，男性和女性的生活质量在统计学上均有所改善。多因素分析显示，女性是疼痛部分生活质量恶化的独立预测因素[P=0.001，比值比（OR）=3.93，95%置信区间（CI）1.74-8.88]。
结论
与男性相比，女性术前和术后生活质量较差。女性性别是CABG术后6个月生活质量恶化的独立预测因素。
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