Department of Orthopaedics and Rehabilitation, Loyola University Health System, Maywood, IL, USA.
J Am Acad Orthop Surg. 2009 Dec;17(12):737-43. doi: 10.5435/00124635-200912000-00002.
Musculoskeletal tumors, both primary neoplasms and metastatic lesions, present a therapeutic challenge for the physician who wishes to provide palliative pain relief using the least invasive approach. The increasing sophistication of imaging modalities such as CT in precisely localizing neoplasm, coupled with the widespread use of radiofrequency ablation (RFA) for treatment of other types of tumor, has generated interest in using RFA to treat musculoskeletal tumors. Primary bone tumors (eg, osteoid osteoma) and metastatic bone tumors have been successfully treated with RFA. Success rates with RFA are equal to those with standard surgical curettage, but RFA has the advantage of decreased surgical morbidity. The procedure is relatively safe, is well-tolerated by the patient, and typically can be performed on an outpatient basis. The most common serious complication reported is localized skin necrosis, which occurs rarely. RFA appears to be a viable minimally invasive approach for palliative treatment of selected bone tumors.
肌肉骨骼肿瘤，包括原发性肿瘤和转移性病变，对于希望采用微创方法提供姑息性疼痛缓解的医生来说是一个治疗挑战。随着 CT 等成像方式的日益精确，可以精确定位肿瘤，加上射频消融 (RFA) 治疗其他类型肿瘤的广泛应用，人们对使用 RFA 治疗肌肉骨骼肿瘤产生了兴趣。原发性骨肿瘤（例如骨样骨瘤）和转移性骨肿瘤已成功接受 RFA 治疗。RFA 的成功率与标准手术刮除术相当，但 RFA 的优点是手术发病率降低。该手术相对安全，患者耐受性良好，通常可以在门诊进行。报告的最常见严重并发症是局部皮肤坏死，很少发生。RFA 似乎是一种可行的微创方法，可用于姑息治疗选定的骨肿瘤。
