双相 I 型心境发作的经验性类型学。
Empirical typology of bipolar I mood episodes.
作者信息
Solomon David A, Leon Andrew C, Endicott Jean, Coryell William H, Li Chunshan, Fiedorowicz Jess G, Keller Martin B
机构信息
Department of Psychiatry, Rhode Island Hospital, 593 Eddy Street, Providence, Rhode Island 02903-4970, USA.
出版信息
Br J Psychiatry. 2009 Dec;195(6):525-30. doi: 10.1192/bjp.bp.108.062083.
BACKGROUND
Much remains unknown about the phenomenology of bipolar I disorder.
AIMS
To determine the type of bipolar I mood episodes that occur over time, and their relative frequency.
METHOD
A total of 219 individuals with Research Diagnostic Criteria bipolar I disorder were prospectively followed for up to 25 years (median 20 years). Psychopathology was assessed with the Longitudinal Interval Follow-up Evaluation.
RESULTS
Overall, 1208 mood episodes were prospectively observed. The episodes were empirically classified as follows: major depression, 30.9% (n = 373); minor depression, 13.0% (n = 157); mania, 20.4% (n = 246); hypomania, 10.4% (n = 126); cycling, 17.3% (n = 210); cycling plus mixed state, 7.8% (n = 94); and mixed, 0.2% (n = 2).
CONCLUSIONS
Cycling episodes constituted 25% of all episodes. Work groups revising ICD-10 and DSM-IV should add a category for bipolar I cycling episode.
背景
关于双相I型障碍的现象学仍有许多未知之处。
目的
确定随时间推移发生的双相I型心境发作的类型及其相对频率。
方法
对总共219例符合研究诊断标准的双相I型障碍患者进行了长达25年（中位数20年）的前瞻性随访。采用纵向间隔随访评估法评估精神病理学情况。
结果
总体而言，前瞻性观察到1208次心境发作。这些发作根据经验分类如下：重度抑郁，30.9%（n = 373）；轻度抑郁，13.0%（n = 157）；躁狂，20.4%（n = 246）；轻躁狂，10.4%（n = 126）；循环发作，17.3%（n = 210）；循环发作加混合状态，7.8%（n = 94）；以及混合发作，0.2%（n = 2）。
结论
循环发作占所有发作的25%。修订ICD - 10和DSM - IV的工作组应增加双相I型循环发作这一类别。
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