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健康婴儿的抗逆转录病毒相关血液学短期毒性：新的新生儿 4 周齐多夫定方案的影响。

Antiretroviral-related hematologic short-term toxicity in healthy infants: implications of the new neonatal 4-week zidovudine regimen.

机构信息

Department of Pediatrics, Pediatric Infectious Diseases Unit, Hospital Sant Joan de Déu-Universitat de Barcelona, Barcelona, Spain.

出版信息

Pediatr Infect Dis J. 2010 Apr;29(4):376-9. doi: 10.1097/INF.0b013e3181c81fd4.

DOI:10.1097/INF.0b013e3181c81fd4
PMID:19949355
Abstract

Recent updates of the guidelines on the prevention of human immunodeficiency virus mother-to-child transmission have shortened the neonatal zidovudine prophylactic regimens from 6 to 4 weeks. We present a prospective observational study in a large cohort of mother-infant pairs and report that the 4-week regimen allows an earlier recovery of the anemia in these otherwise healthy infants.

摘要

最近更新的人类免疫缺陷病毒母婴传播预防指南将新生儿齐多夫定预防性方案从 6 周缩短至 4 周。我们在一个大型母婴队列中进行了前瞻性观察研究，并报告说，4 周方案可使这些原本健康的婴儿更早地恢复贫血。

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