拉福拉病作为犬视觉性加重性肌阵挛发作的一个病因。
Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog.
作者信息
Webb Aubrey A, McMillan Chantal, Cullen Cheryl L, Boston Sarah E, Turnbull Julie, Minassian Berge A
机构信息
Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, 3330 Hospital Drive, NW, Calgary, Alberta T2N 4N1.
出版信息
Can Vet J. 2009 Sep;50(9):963-7.
Abstract
An 8-year-old, castrated male, miniature wire-haired dachshund was presented with a 4-month history of intermittent facial twitching (myoclonus). The myoclonic episodes progressed over a 16-month period. Generalized seizure activity was infrequent. Clinical examination revealed visually stimulated myoclonus. Response to therapy with antiepileptic drugs was equivocal. Genetic testing identified the dog as being affected by Lafora disease.
摘要
一只8岁去势雄性迷你刚毛腊肠犬出现间歇性面部抽搐（肌阵挛）4个月病史。肌阵挛发作在16个月内逐渐进展。全身性癫痫发作活动不常见。临床检查发现视觉刺激诱发的肌阵挛。抗癫痫药物治疗反应不明确。基因检测确定该犬患有拉福拉病。
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