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髋关节和膝关节置换手术需求建模。第2部分。纳入人口普查数据以提供带有不确定性界限的小区域需求预测。

Modeling the need for hip and knee replacement surgery. Part 2. Incorporating census data to provide small-area predictions for need with uncertainty bounds.

作者信息

Judge Andy, Welton Nicky J, Sandhu Jat, Ben-Shlomo Yoav

机构信息

University of Bristol, Bristol, UK.

出版信息

Arthritis Rheum. 2009 Dec 15;61(12):1667-73. doi: 10.1002/art.24732.

Abstract

OBJECTIVE

To develop methods to produce small-area estimates of need for hip and knee replacement surgery to inform local health service planning.

METHODS

Multilevel Poisson regression modeling was used to estimate rates of need for hip/knee replacement by age, sex, deprivation, rurality, and ethnic mix using a nationally representative population-based survey (the English Longitudinal Study of Ageing, n = 11,392 people age > or =50 years). Estimates of need from the regression model were then combined with stratified census population counts to produce small-area predictions of need. Uncertainty in the predictions was obtained by taking a Bayesian simulation-based approach using WinBUGS software. This allows correlations in parameter estimates to be appropriately incorporated in the credible intervals for the small-area predictions.

RESULTS

Small-area estimates of need for hip/knee replacement have been produced for wards and districts in England. Rates of need are adjusted for the sociodemographic characteristics of an area and include 95% credible intervals. Need for hip/knee replacement varies geographically, dependant on the sociodemographic characteristics of an area.

CONCLUSION

For the first time, small-area estimates of need for hip/knee replacement surgery have been produced together with estimates of uncertainty to inform local health planning. The methodologic approach described here could be reproduced in other countries and for other disease indicators. Further research is required to combine small-area estimates of need with provision to determine whether there is equitable access to care.

摘要

目的

开发用于生成髋关节和膝关节置换手术需求小区域估计值的方法,为地方卫生服务规划提供信息。

方法

采用多级泊松回归模型,利用一项具有全国代表性的基于人群的调查(英国老龄化纵向研究,n = 11392名年龄≥50岁的人),按年龄、性别、贫困程度、农村地区和种族构成估计髋关节/膝关节置换的需求率。然后将回归模型得出的需求估计值与分层的人口普查人口数相结合,以生成需求的小区域预测值。预测中的不确定性通过使用WinBUGS软件采用基于贝叶斯模拟的方法获得。这使得参数估计中的相关性能够被适当地纳入小区域预测的可信区间。

结果

已得出英格兰各病房和地区髋关节/膝关节置换需求的小区域估计值。需求率根据一个地区的社会人口特征进行了调整,并包括95%的可信区间。髋关节/膝关节置换的需求因地区而异,取决于一个地区的社会人口特征。

结论

首次生成了髋关节/膝关节置换手术需求的小区域估计值以及不确定性估计值,为地方卫生规划提供信息。此处描述的方法学方法可在其他国家和针对其他疾病指标进行重现。需要进一步开展研究,将需求的小区域估计值与服务提供情况相结合,以确定是否能公平获得医疗服务。

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