Cecka Filip, Jon Bohumil, Hatlová Jana, Tycová Vera, Neoral Cestmír, Ferko Alexander, Melichar Bohuslav
Department of Surgery, Charles University Medical School Teaching Hospital, Hradec Králové, Czech Republic.
Hepatogastroenterology. 2009 Sep-Oct;56(94-95):1529-32.
BACKGROUND/AIMS: Metastatic renal cell carcinoma (RCC) is a malignant tumor characterized by great variation in the clinical course and unusual sites of metastases. Metastases to the pancreas are, in general, rare.
A retrospective chart review of patients treated a single institution.
Single center experience in 10 patients with this rare presentation of metastatic RCC is presented. In most cases, the course after diagnosis of RCC pancreas metastases was relatively favorable, specifically in patients treated with surgical removal of the metastases. The median survival from the diagnosis of RCC pancreas metastases was 56 months.
The course of disease in patients with RCC pancreas metastases is often indolent. Long-term survival may be obtained after surgery even with suboptimal systemic therapy. An active therapeutic approach is warranted in these patients.
背景/目的:转移性肾细胞癌(RCC)是一种恶性肿瘤,其临床病程差异很大,转移部位也不寻常。胰腺转移一般较为罕见。
对在单一机构接受治疗的患者进行回顾性病历审查。
介绍了单中心10例转移性RCC这种罕见表现患者的经验。在大多数情况下,肾细胞癌胰腺转移诊断后的病程相对较好,特别是在接受转移灶手术切除的患者中。从肾细胞癌胰腺转移诊断后的中位生存期为56个月。
肾细胞癌胰腺转移患者的病程通常进展缓慢。即使全身治疗欠佳,手术后也可能获得长期生存。对这些患者应采取积极的治疗方法。