Demirkaya Erkan, Cakmakli Hasan Fatih, Güçer Safak, Aktay-Ayaz Nuray, Gürgey Aytemiz, Ozen Seza
Units of Pediatric Rheumatology and Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2009 Jul-Aug;51(4):378-80.
We present a 12-year-old girl with systemic lupus erythematosus and associated antiphospholipid syndrome who developed an unusual manifestation of purpura fulminans in an accelerated fashion. The patient improved after prompt treatment with anticoagulants, aggressive immunosuppressive drugs and plasmapheresis. This is the first pediatric case of purpura fulminans due to secondary antiphospholipid syndrome of systemic lupus erythematosus. We suggest that SLE patients with lupus anticoagulant should be followed closely for similar complications.
我们报告一名12岁患有系统性红斑狼疮及相关抗磷脂综合征的女孩，她迅速出现了暴发性紫癜这一不寻常表现。经抗凝剂、积极的免疫抑制药物及血浆置换迅速治疗后，患者病情好转。这是首例因系统性红斑狼疮继发抗磷脂综合征导致暴发性紫癜的儿科病例。我们建议，对患有狼疮抗凝物的系统性红斑狼疮患者应密切随访，以观察是否出现类似并发症。
