Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS and Center for Infection and Immunity, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Clin Infect Dis. 2010 Jan 1;50(1):80-3. doi: 10.1086/648726.
In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSb(v)), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSb(v), and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients.
在一项涉及 34 例利什曼原虫感染患者的回顾性观察研究中，31 例患者曾接受过局部注射锑（ilSb(v)）治疗但未成功，米替福新被证明是有效的。30 例患者接受米替福新治疗后痊愈，3 例患者在接受额外的局部注射锑（ilSb(v)）治疗后痊愈，1 例患者在接受 28 天的每日静脉注射锑治疗后痊愈。21 例患者报告说精液量暂时减少。
