Capon Alexandre, Iarmarcovai Gwen, Mordon Serge
CHRU, Lille, France.
J Cosmet Laser Ther. 2009 Dec;11(4):220-3. doi: 10.3109/14764170903352878.
Laser-Assisted Skin Healing (LASH) is based on the therapeutic effects of controlled thermal post-conditioning. The authors have previously demonstrated on humans that an 810-nm diode-laser system could assist wound closure leading to an improvement of wound healing with a resulting indiscernible scar. A 47-year-old woman (skin type II), who developed systematically hypertrophic scars after surgery, was enrolled for a hypertrophic scar revision. Excess scar tissue was removed. Immediately after the conventional closure of the incision, laser irradiation (120 J/cm(2)) using a 0.8 cm(2) spot size (rectangular spot, length = 20 mm, width = 4 mm) was applied. Topical silicone gel sheeting (Cerederm((R))) was applied for 2 months afterwards to prevent a thick scar from reforming. No complications occurred during the course of this study. No recurrence of hypertrophic scarring was noticed 6 months after scar revision. This study reports, for the first time, the possibility of improving the appearance of hypertrophic scarring in scar revision by altering through thermal stress the wound-healing process. Since the appropriate initial management of wounds is of importance, the LASH technique could be offered as a new approach to prevent hypertrophic scarring.
激光辅助皮肤愈合（LASH）基于可控热后处理的治疗效果。作者此前已在人体上证明，810纳米二极管激光系统可辅助伤口闭合，促进伤口愈合，最终形成难以察觉的疤痕。一名47岁女性（II型皮肤），术后系统性出现增生性疤痕，入组接受增生性疤痕修复治疗。切除多余的疤痕组织。在常规缝合切口后，立即使用光斑尺寸为0.8平方厘米（矩形光斑，长 = 20毫米，宽 = 4毫米）进行激光照射（120焦耳/平方厘米）。之后使用外用硅胶片（Cerederm®）2个月，以防止形成增厚的疤痕。本研究过程中未发生并发症。疤痕修复6个月后未发现增生性疤痕复发。本研究首次报道了通过热应力改变伤口愈合过程来改善疤痕修复中增生性疤痕外观的可能性。由于伤口的适当初始处理很重要，LASH技术可作为预防增生性疤痕的一种新方法。
