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[一例胰腺胸膜瘘致复发性大量血性胸腔积液]

[Recurrent massive bloody pleural effusion caused by pancreatic pleural fistula in a case].

作者信息

Li Hui-min, Zhao Shun-ying, Zhou Jin, Zeng Qi, Zeng Jin-jin, Jiang Zai-fang

机构信息

Department of Pediatric Internal Medicine, Beijing Children's Hospital Affiliated to Capital Medical University, Be4iing 100045, China.

出版信息

Zhonghua Er Ke Za Zhi. 2009 Aug;47(8):621-3.

Abstract

OBJECTIVE

To introduce the early clinical features and the main points of diagnosis and treatment of children with pancreatic pleural fistula presenting massive bloody pleural effusion.

METHOD

The clinical data of symptoms, signs, laboratory examination, diagnosis and treatment methods of pancreatic pleural fistula in a child are presented.

RESULT

A 4-year-old boy presented with one month history of intermittent fever, cough, chest tightness and chest pain. His pleural effusion collected from three thoracic closed drainage was hemorrhagic. He had no positive abdominal signs. His abdominal B-mode ultrasonography showed rough pancreatic echo. The levels of amylase in blood and pleural fluid were 495 U/L and 35 938 U/L, respectively. There was a fistulous tract from the thoracic cavity leading to the pancreas at thoracic surgical exploration. The child was cured by total parenteral nutrition, intravenous infusion of somatostatin and a stent placed in the pancreatic duct by endoscopic retrograde cholangiopancreatography (ERCP).

CONCLUSION

The child with pancreatic pleural fistula in early stage mainly present respiratory symptoms and lack abdominal symptoms, so the diagnosis and treatment is often delayed. Significant increase of pancreatic amylase level in pleural effusion can be an important clue and basis for the diagnosis. If conservative therapy fails, the examination and treatment with ERCP should be considered.

摘要

目的

介绍以大量血性胸腔积液为表现的儿童胰胸膜瘘的早期临床特征及诊治要点。

方法

呈现1例儿童胰胸膜瘘的症状、体征、实验室检查、诊断及治疗方法等临床资料。

结果

1名4岁男孩有1个月间歇性发热、咳嗽、胸闷及胸痛病史。经3次胸腔闭式引流引出的胸腔积液为血性。其腹部无阳性体征。腹部B超显示胰腺回声粗糙。血液及胸腔积液淀粉酶水平分别为495 U/L和35 938 U/L。胸腔手术探查发现胸腔有瘘管通向胰腺。该患儿经全胃肠外营养、静脉输注生长抑素及通过内镜逆行胰胆管造影术(ERCP)在胰管内置入支架后治愈。

结论

胰胸膜瘘患儿早期主要表现为呼吸道症状,缺乏腹部症状,故诊治常被延误。胸腔积液中胰淀粉酶水平显著升高可为诊断的重要线索和依据。若保守治疗无效,应考虑行ERCP检查及治疗。

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