Hounsa A, Kouadio L, De Mol P
Service de microbiologie médicale, centre hospitalier universitaire de Liège, domaine universitaire du Sart-Tilman, université de Liège, bâtiment B23, avenue de l'Hôpital, Liège, Belgique.
Med Mal Infect. 2010 Jun;40(6):333-40. doi: 10.1016/j.medmal.2009.10.002. Epub 2009 Nov 29.
Self-medication with antibiotics is all the more disturbing in developing countries where this type of medication is easily available, and often without any prescription.
The authors wanted to assess and describe self-medication with antibiotics and identify the factors and public perception associated with this type of self-medication.
Eighteen private pharmacies were randomly selected in Abidjan. Data was collected through structured questionnaires and reports. Group meetings were organized for private pharmacy clients and the pharmacy staff.
Two hundred and forty-two out of 1,123 purchases of antibiotics were for self-medication (21.5 %). Out of the 1,765 people interviewed, 1,054 (59.7 %) had bought antibiotics for self-medication in the 12 months prior to our study. Pharmacy staff very rarely provided any information to purchasers concerning dose, when to take the medicine, or treatment duration. A logistic regression analysis showed that the probability of self-medication with antibiotics increased with several factors: age, education level, and the possibility of purchasing antibiotics on the marketplace. However, this risk decreased when patients were covered by medical insurance, when the public perceived the risks of self-medication, and when bacterial resistance was clearly defined.
This study was the first in the Ivory Coast to analyze the factors involved in antibiotic self-medication. It stressed the need to establish sustainable interventions to control the antibiotic use.
在发展中国家，自行使用抗生素的现象愈发令人担忧，因为这类药物很容易获得，而且常常无需处方。
作者想要评估和描述自行使用抗生素的情况，并确定与此类自行用药相关的因素及公众认知。
在阿比让随机选择了18家私人药店。通过结构化问卷和报告收集数据。为私人药店顾客和药店工作人员组织了小组会议。
在1123次抗生素购买中，有242次是用于自行用药（21.5%）。在接受采访的1765人中，1054人（59.7%）在我们研究前的12个月内购买过抗生素用于自行用药。药店工作人员很少向购买者提供有关剂量、服药时间或疗程的任何信息。逻辑回归分析表明，自行使用抗生素的可能性会因几个因素而增加：年龄、教育水平以及在市场上购买抗生素的可能性。然而，当患者有医疗保险、公众意识到自行用药的风险以及明确界定细菌耐药性时，这种风险会降低。
这项研究是科特迪瓦首次分析抗生素自行用药所涉及的因素。它强调了建立可持续干预措施以控制抗生素使用的必要性。
