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[慢性阻塞性肺疾病中BDI/TDI评分的验证研究]

[Validation study of the BDI/TDI scores in chronic obstructive pulmonary disease].

作者信息

Laurendeau C, Pribil C, Perez T, Roche N, Simeoni M-C, Detournay B

机构信息

CEMKA, Bourg La Reine, France.

出版信息

Rev Mal Respir. 2009 Sep;26(7):735-43. doi: 10.1016/s0761-8425(09)72424-6.

Abstract

BACKGROUND

The Baseline and Transition Dyspnoea Indices (BDI/TDI) provide measurements of breathlessness and of its impact on activities of daily living.

OBJECTIVES

To assess, in France, the measurement characteristics of the BDI/TDI scores.

METHOD

A multicentric cohort of 103 patients with mild to severe COPD was questioned by both a medical and a paramedical investigator at enrollment and again 6 months later.

RESULTS

Concordance between investigators was good for all the sub-scores of the BDI, but less satisfactory for the TDI score. The BDI score was significantly correlated with all spirometric data. Conversely, the TDI score only correlated significantly with change in the FEV1. Both scores correlated highly with the modified Medical Research Council score, the St George Respiratory Questionnaire and with their evolution. The average TDI score was close to 0 in stable patients indicating good reproducibility of this Index. Changes in the TDI score were closely associated with changes in global health assessment by physicians, less so when assessed by patients.

CONCLUSION

The BDI-TDI scores appear to be valid instruments for the measurement of dyspnoea in COPD patients and, less significantly, for measurement of its change over time.

摘要

背景

基线和过渡性呼吸困难指数(BDI/TDI)用于测量呼吸困难及其对日常生活活动的影响。

目的

在法国评估BDI/TDI评分的测量特征。

方法

对103例轻至重度慢性阻塞性肺疾病(COPD)患者组成的多中心队列进行研究,在入组时由医学和辅助医疗研究人员分别进行询问,6个月后再次询问。

结果

研究人员之间对于BDI所有子评分的一致性良好,但对于TDI评分的一致性不太令人满意。BDI评分与所有肺功能数据显著相关。相反,TDI评分仅与第一秒用力呼气容积(FEV1)的变化显著相关。两个评分均与改良的医学研究委员会评分、圣乔治呼吸问卷及其变化高度相关。稳定患者的平均TDI评分为0左右,表明该指数具有良好的可重复性。TDI评分的变化与医生对整体健康状况的评估变化密切相关,而患者评估时相关性较弱。

结论

BDI-TDI评分似乎是测量COPD患者呼吸困难的有效工具,而测量其随时间的变化有效性稍弱。

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