Are macrolides now obligatory in severe community-acquired pneumonia?

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作者信息

Waterer Grant W

出版信息

Intensive Care Med. 2010 Apr;36(4):562-4. doi: 10.1007/s00134-009-1734-7. Epub 2009 Dec 2.

DOI:10.1007/s00134-009-1734-7

PMID:19953221

Abstract

摘要

相似文献

Are macrolides now obligatory in severe community-acquired pneumonia?

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Septic shock from community-onset pneumonia: is there a role for aspirin plus macrolides combination?社区获得性肺炎所致感染性休克：阿司匹林联合大环内酯类药物是否有效？

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Is azithromycin the first-choice macrolide for treatment of community-acquired pneumonia?阿奇霉素是治疗社区获得性肺炎的首选大环内酯类药物吗？

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Macrolides are associated with a better survival rate in patients hospitalized with community-acquired but not healthcare-associated pneumonia.大环内酯类药物与社区获得性肺炎而非医疗保健相关性肺炎住院患者的较高生存率相关。

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引用本文的文献

Questions remain regarding mandatory use of macrolides in community-acquired pneumonia.关于在社区获得性肺炎中强制使用大环内酯类药物仍存在一些问题。

Intensive Care Med. 2010 Oct;36(10):1787. doi: 10.1007/s00134-010-1950-1. Epub 2010 Jul 15.

本文引用的文献

Intensive Care Med. 2010 Apr;36(4):612-20. doi: 10.1007/s00134-009-1730-y. Epub 2009 Dec 2.

Effect of macrolide and fluoroquinolone antibacterials on the risk of ventricular arrhythmia and cardiac arrest: an observational study in Italy using case-control, case-crossover and case-time-control designs.大环内酯类和氟喹诺酮类抗菌药物对室性心律失常和心脏骤停风险的影响：在意大利进行的一项采用病例对照、病例交叉和病例时间对照设计的观察性研究。

Drug Saf. 2009;32(2):159-67. doi: 10.2165/00002018-200932020-00008.

Efficacy of the combination of tachyplesin III and clarithromycin in rat models of Escherichia coli sepsis.鲎素III与克拉霉素联合用药对大肠杆菌败血症大鼠模型的疗效

Antimicrob Agents Chemother. 2008 Dec;52(12):4351-5. doi: 10.1128/AAC.00086-08. Epub 2008 Sep 8.

Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia.大环内酯类药物治疗对肺炎所致严重脓毒症患者死亡率的影响。

Eur Respir J. 2009 Jan;33(1):153-9. doi: 10.1183/09031936.00054108. Epub 2008 Sep 3.

Effect of clarithromycin in patients with sepsis and ventilator-associated pneumonia.克拉霉素对脓毒症合并呼吸机相关性肺炎患者的疗效

Clin Infect Dis. 2008 Apr 15;46(8):1157-64. doi: 10.1086/529439.

Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro.大环内酯类、阿莫西林、头孢曲松、多西环素、妥布霉素和氟喹诺酮类药物对肺炎链球菌体外产生肺炎溶血素的影响比较。

J Antimicrob Chemother. 2007 Nov;60(5):1155-8. doi: 10.1093/jac/dkm338. Epub 2007 Sep 10.

Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock.联合抗生素治疗可提高社区获得性肺炎合并休克患者的生存率。

Crit Care Med. 2007 Jun;35(6):1493-8. doi: 10.1097/01.CCM.0000266755.75844.05.

Antibiotics for bacteremic pneumonia: Improved outcomes with macrolides but not fluoroquinolones.用于菌血症性肺炎的抗生素：大环内酯类药物可改善预后，但氟喹诺酮类药物则不然。

Chest. 2007 Feb;131(2):466-73. doi: 10.1378/chest.06-1426.

The impact of empiric antimicrobial therapy with a β-lactam and fluoroquinolone on mortality for patients hospitalized with severe pneumonia.经验性使用β-内酰胺类和氟喹诺酮类抗菌药物治疗对住院严重肺炎患者死亡率的影响。

Crit Care. 2005 Dec 6;10(1):R8. doi: 10.1186/cc3934.

Immunomodulatory effects of antimicrobials in the therapy of respiratory tract infections.抗菌药物在呼吸道感染治疗中的免疫调节作用。

Curr Opin Infect Dis. 2005 Apr;18(2):125-31. doi: 10.1097/01.qco.0000160901.71813.fe.

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