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儿童慢性腹膜透析相关性嗜酸性粒细胞性腹膜炎。

Eosinophilic peritonitis in children on chronic peritoneal dialysis.

机构信息

Department of Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, WC1N 3JH, UK.

出版信息

Pediatr Nephrol. 2010 Mar;25(3):517-22. doi: 10.1007/s00467-009-1366-8. Epub 2009 Dec 2.

DOI:10.1007/s00467-009-1366-8
PMID:19953276
Abstract

Eosinophilic peritonitis is a response of the peritoneum to foreign substances. It presents as cloudy dialysate and may be missed because not all laboratories report the eosinophil count, giving only the total number of polymorphonuclear cells. Over a 2-year period, eight children developed 13 episodes of eosinophilic peritonitis. Three episodes were asymptomatic other than cloudy fluid, five followed surgery and two were associated with gastroenteritis. Despite recurrent episodes, there were no adverse outcomes, although a raised peritoneal eosinophil count persisted in most cases. Eosinophilic peritonitis is under-diagnosed and may lead to unnecessary antibiotic therapy.

摘要

嗜酸性粒细胞性腹膜炎是腹膜对异物的反应。其表现为混浊的透析液,可能会被漏诊,因为并非所有实验室都报告嗜酸性粒细胞计数,而仅报告总中性粒细胞数。在 2 年期间,8 名儿童出现 13 次嗜酸性粒细胞性腹膜炎发作。除了混浊的液体外,有 3 次发作无症状,5 次发作与手术后有关,2 次与肠胃炎有关。尽管反复发作,但没有不良后果,尽管大多数情况下腹膜嗜酸性粒细胞计数仍然升高。嗜酸性粒细胞性腹膜炎诊断不足,可能导致不必要的抗生素治疗。

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Eosinophilic peritonitis in children on chronic peritoneal dialysis.儿童慢性腹膜透析相关性嗜酸性粒细胞性腹膜炎。
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Beijing Da Xue Xue Bao Yi Xue Ban. 2018 Aug 18;50(4):747-751.
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Eosinophilic peritonitis.嗜酸性粒细胞性腹膜炎
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Peritoneal eosinophils during intermittent peritoneal dialysis.间歇性腹膜透析期间的腹膜嗜酸性粒细胞
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Perit Dial Int. 2003 Sep-Oct;23(5):460-4.
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"Eosinophilic" peritonitis in continuous ambulatory peritoneal dialysis (CAPD).持续性非卧床腹膜透析(CAPD)中的“嗜酸性粒细胞性”腹膜炎
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引用本文的文献

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Regulation of chemokine CCL5 synthesis in human peritoneal fibroblasts: a key role of IFN-γ.调控人腹膜成纤维细胞趋化因子 CCL5 的合成:IFN-γ 的关键作用。
Mediators Inflamm. 2014;2014:590654. doi: 10.1155/2014/590654. Epub 2014 Jan 9.
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Montelukast: a novel therapeutic option in eosinophilic peritonitis.孟鲁司特:嗜酸性粒细胞性腹膜炎的一种新型治疗选择。

本文引用的文献

1
Cloudy peritoneal dialysate: it's not always infection.浑浊的腹膜透析液:并非总是由感染引起。
Contrib Nephrol. 2006;150:187-194. doi: 10.1159/000093594.
2
Eosinophilic peritonitis in a patient with continuous ambulatory peritoneal dialysis (CAPD).一名持续非卧床腹膜透析(CAPD)患者的嗜酸性粒细胞性腹膜炎。
Korean J Intern Med. 2004 Jun;19(2):121-3. doi: 10.3904/kjim.2004.19.2.121.
3
Severe peritoneal mononucleosis associated with icodextrin use in continuous ambulatory peritoneal dialysis.与持续非卧床腹膜透析中使用艾考糊精相关的严重腹膜单核细胞增多症
Pediatr Nephrol. 2014 Jul;29(7):1279-82. doi: 10.1007/s00467-013-2718-y. Epub 2013 Dec 18.
4
Consensus guidelines for the prevention and treatment of catheter-related infections and peritonitis in pediatric patients receiving peritoneal dialysis: 2012 update.小儿腹膜透析患者导管相关感染和腹膜炎预防与治疗的共识指南:2012年更新版
Perit Dial Int. 2012 Jun;32 Suppl 2(Suppl 2):S32-86. doi: 10.3747/pdi.2011.00091.
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Incidence and significance of peritoneal eosinophilia during peritoneal dialysis-related peritonitis.腹膜透析相关性腹膜炎期间腹膜嗜酸性粒细胞增多症的发生率及意义。
Perit Dial Int. 2003 Sep-Oct;23(5):460-4.
5
Specific characteristics of peritoneal leucocyte populations during sterile peritonitis associated with icodextrin CAPD fluids.与艾考糊精持续性非卧床腹膜透析液相关的无菌性腹膜炎期间腹膜白细胞群体的特定特征。
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Relapsing culture-negative peritonitis in peritoneal dialysis patients exposed to icodextrin solution.接受艾考糊精溶液治疗的腹膜透析患者复发性培养阴性腹膜炎
Am J Kidney Dis. 2002 Nov;40(5):1030-5. doi: 10.1053/ajkd.2002.36341.
7
Resolution of eosinophilic peritonitis with ketotifen.酮替芬治疗嗜酸性粒细胞性腹膜炎有效。
Am J Kidney Dis. 1997 Sep;30(3):433-6. doi: 10.1016/s0272-6386(97)90290-0.
8
Peritoneal eosinophils during intermittent peritoneal dialysis.间歇性腹膜透析期间的腹膜嗜酸性粒细胞
Am J Nephrol. 1984;4(3):152-7. doi: 10.1159/000166796.
9
Intraperitoneal hydrocortisone in eosinophilic peritonitis associated with continuous ambulatory peritoneal dialysis.嗜酸性腹膜炎伴持续非卧床腹膜透析时腹腔内注射氢化可的松
Br Med J (Clin Res Ed). 1983 Mar 5;286(6367):766. doi: 10.1136/bmj.286.6367.766.
10
Eosinophilia of peritoneal fluid and peripheral blood associated with chronic peritoneal dialysis.与慢性腹膜透析相关的腹腔积液和外周血嗜酸性粒细胞增多症。
Am J Clin Pathol. 1967 May;47(5):638-40. doi: 10.1093/ajcp/47.5.638.