Piraino B M, Silver M R, Dominguez J H, Puschett J B
Am J Nephrol. 1984;4(3):152-7. doi: 10.1159/000166796.
Peritoneal eosinophil counts were investigated in 61 intermittent dialysis patients over the course of 1 year. The peritoneal eosinophil percentage fell from 18 +/- 2% (mean +/- SEM) in the first 2 months of dialysis to 3 +/- 0.4% after 6 months of dialysis. Absolute eosinophils per cubic millimeter fell from 586 +/- 126 to 61 +/- 18 (p less than 0.01 for both percentage and absolute values). There was a wide range in the mean eosinophil percentages per patient in the first 6 months of dialysis (0-84%) that narrowed to 0-9% after 6 months. The majority of the high initial eosinophil counts resolved after 2 months. Peripheral eosinophilia was seen in 8 of the 10 patients with the highest mean peritoneal eosinophil percentages during the first 2 months of dialysis. Patients who developed peritonitis had a significantly lower percentage of eosinophils in the first 1.5 months of dialysis than patients who did not develop peritonitis. At the time of diagnosis of peritonitis, the peritoneal eosinophil count was near zero. 4 cases of peritoneal eosinophilia which developed after antibiotic therapy are described.
在1年的时间里，对61例间歇性透析患者的腹腔嗜酸性粒细胞计数进行了调查。透析前2个月，腹腔嗜酸性粒细胞百分比从18±2%（平均值±标准误）降至透析6个月后的3±0.4%。每立方毫米的绝对嗜酸性粒细胞数从586±126降至61±18（百分比和绝对值均P<0.01）。透析前6个月每位患者的平均嗜酸性粒细胞百分比范围很广（0-84%），6个月后缩小至0-9%。大多数初始嗜酸性粒细胞计数较高的情况在2个月后消失。在透析前2个月平均腹腔嗜酸性粒细胞百分比最高的10例患者中，有8例出现外周嗜酸性粒细胞增多。发生腹膜炎的患者在透析的前1.5个月嗜酸性粒细胞百分比显著低于未发生腹膜炎的患者。在诊断腹膜炎时，腹腔嗜酸性粒细胞计数接近零。本文描述了4例抗生素治疗后发生的腹腔嗜酸性粒细胞增多症病例。
