Hopkins I J, Klug G L
Royal Children's Hospital, Melbourne, Australia.
Dev Med Child Neurol. 1991 Jan;33(1):26-31. doi: 10.1111/j.1469-8749.1991.tb14782.x.
Eleven patients with intractable complex partial seizures underwent temporal lobectomy during their first decade. The mean age at onset of epilepsy was two years and at surgery was 5.5 years. On the basis of data from clinical evaluation, CT, MRI in six patients, and pathological examination of excised tissue, the aetiology of the epilepsy was thought to be mesial temporal sclerosis in four children, glioma in five, dysplasia in one and chronic progressive encephalitis in another. At follow-up eight children were seizure-free, two had reduced seizure frequency and only the child with chronic progressive encephalitis had not benefitted from surgery.
11例难治性复杂部分性癫痫患者在其十岁前接受了颞叶切除术。癫痫发作的平均起始年龄为2岁，手术时的平均年龄为5.5岁。根据临床评估、6例患者的CT和MRI以及切除组织的病理检查数据，认为4例儿童癫痫的病因是内侧颞叶硬化，5例是胶质瘤，1例是发育异常，另1例是慢性进行性脑炎。随访时，8例儿童无癫痫发作，2例癫痫发作频率降低，只有患有慢性进行性脑炎的儿童未从手术中获益。
