Department of Obstetrics, Charité - Universitätsmedizin Berlin, Berlin, Germany.
J Perinat Med. 2010;38(1):83-6. doi: 10.1515/jpm.2010.006.
To determine the predictive value of fetal pulse oximetry (FPO) for the development of fetal acidosis in cases of non-reassuring fetal heart rate (FHR).
In a prospective observational study, pulse oximetry monitoring was examined in cases of non-reassuring FHR during singleton cephalic delivery at 36-42 weeks' gestation. The study examined whether fetal arterial oxygen saturation (FSpO(2)) values <30% for at least 10 min during the last 60 min before delivery increase the risk of fetal acidosis. The predictive reliability of this algorithm and the correlation to fetal acidosis [umbilical artery pH (UApH) <7.15] were analyzed.
We included 101 patients with non-reassuring FHR during delivery. The incidence of fetal acidosis was significantly higher when FSpO(2) values <30% were recorded for at least 10 min (P=0.0). An UApH <7.15 was reliably excluded with a negative predictive value of 98.7% and detected with a sensitivity of 92.9%.
A low pulse oximetry oxygen saturation <30% for at least 10 min correlates highly with fetal acidosis in cases of non-reassuring FHR. FPO reliably excludes moderate to advanced acidosis and can reduce the frequency of fetal blood analysis (FBA) in cases of non-reassuring cardiotocography (CTG).
确定胎儿脉搏血氧饱和度(FPO)在非反应性胎心监护(FHR)情况下预测胎儿酸中毒的价值。
在一项前瞻性观察性研究中,在 36-42 周妊娠的单胎头位分娩中,对非反应性 FHR 进行脉搏血氧监测。该研究检查了在分娩前最后 60 分钟内,胎儿动脉血氧饱和度(FSpO2)值<30%且持续至少 10 分钟是否会增加胎儿酸中毒的风险。分析了该算法的预测可靠性及其与胎儿酸中毒(脐动脉 pH 值<7.15)的相关性。
我们纳入了 101 例分娩时非反应性 FHR 的患者。当记录到 FSpO2 值<30%且持续至少 10 分钟时,胎儿酸中毒的发生率显著更高(P=0.0)。阴性预测值为 98.7%,灵敏度为 92.9%,可靠地排除了 UApH<7.15。
在非反应性 FHR 的情况下,低脉搏血氧饱和度<30%且持续至少 10 分钟与胎儿酸中毒高度相关。FPO 可靠地排除了中度至重度酸中毒,并可以减少非反应性胎心监护(CTG)情况下胎儿血液分析(FBA)的频率。