Pisello F, Geraci G, Arnone E, Modica G, Stassi F, Sciumè C
Sezione di Chirurgia Generale ad Indirizzo Toracico, Università degli Studi di Palermo.
G Chir. 2009 Oct;30(10):440-4.
Colonoscopic surveillance is an established method of colorectal cancer (CRC) screening that reduces death rates, but has an adenoma miss rate of 10-20%. Narrow band imaging (NBI), a novel endoscopic technology, highlights superficial mucosal capillaries and improves contrast for small adenomas. This study evaluated the role of NBI in the improving colon adenoma detection.
White light colonoscope was compared with NBI for adenoma detection during colonoscopy. 120 patients presenting for diagnostic colonoscopy were randomly assigned to undergo colonoscopy using either conventional white light or NBI colonscope during instrument withdrawal. The outcome parameter was the difference in the adenoma detection rate between the two techniques. All polyps detected were removed for histopathological analysis.
Adenomas were detected more frequently in the NBI group (51) than in the control group (49); however, the difference was not statistically significant (p = 0.128). The extubation time was significatively longer in the NBI group (p = 0.003).
In our experience, the NBI did not increased the adenomas detection rate compared to white light by an endoscopist with a known high detection rate using white light.
结肠镜监测是一种成熟的结直肠癌（CRC）筛查方法，可降低死亡率，但腺瘤漏诊率为10%-20%。窄带成像（NBI）是一种新型内镜技术，可突出浅表黏膜毛细血管并改善小腺瘤的对比度。本研究评估了NBI在提高结肠腺瘤检测中的作用。
在结肠镜检查期间，比较白光结肠镜与NBI用于腺瘤检测的情况。120例接受诊断性结肠镜检查的患者在退镜时被随机分配接受使用传统白光结肠镜或NBI结肠镜的检查。结果参数是两种技术之间腺瘤检测率的差异。所有检测到的息肉均被切除以进行组织病理学分析。
NBI组（51例）检测到的腺瘤比对照组（49例）更频繁；然而，差异无统计学意义（p = 0.128）。NBI组的退镜时间明显更长（p = 0.003）。
根据我们的经验，与使用白光具有已知高检测率的内镜医师相比，NBI与白光相比并未提高腺瘤检测率。
