Department of Surgery, Mayo Clinic, Rochester, MN, USA.
Am J Surg. 2010 Apr;199(4):522-8. doi: 10.1016/j.amjsurg.2009.05.019. Epub 2009 Dec 2.
Wire-localized breast biopsy (WLBB) remains the standard method for the surgical excision of nonpalpable breast lesions. Because of many of its shortcomings, most important a high microscopic positive margin rate, alternative approaches have been described, including radioactive seed localization (RSL). This review highlights the literature regarding RSL, including safety, the ease of the procedure, billing, and oncologic outcomes.
Medline and PubMed were searched using the terms "radioactive seed" and "breast." All peer-reviewed studies were included in this review.
RSL is a promising approach for the resection of nonpalpable breast lesions. It is a reliable and safe alternative to WLBB. RSL is at least equivalent compared with WLBB in terms of the ease of the procedure, removing the target lesion, the volume of breast tissue excised, obtaining negative margins, avoiding a second operative intervention, and allowing for simultaneous axillary staging.
经导丝定位的乳腺活检（WLBB）仍然是切除不可触及的乳腺病变的标准方法。由于其许多缺点，最重要的是高的显微镜阳性边缘率，已经描述了替代方法，包括放射性种子定位（RSL）。本综述强调了关于 RSL 的文献，包括安全性、手术的简便性、计费和肿瘤学结果。
使用术语“放射性种子”和“乳房”在 Medline 和 PubMed 上进行搜索。本综述纳入了所有同行评议的研究。
RSL 是切除不可触及的乳腺病变的一种很有前途的方法。它是 WLBB 的可靠和安全的替代方法。在手术的简便性、切除目标病变、切除的乳腺组织量、获得阴性切缘、避免第二次手术干预以及同时进行腋窝分期方面，RSL 与 WLBB 至少是等效的。
