Langhans Linnea, Vejborg Thomas S, Vejborg Ilse, Kroman Niels
Brystkirurgisk Klinik, Rigshospitalet, Afsnit 3104, 2100 København Ø, Denmark.
Ugeskr Laeger. 2012 Aug 20;174(34):1891-4.
The Danish national mammography screening programme leads to identification of an increased number of small non-palpable breast tumours, suitable for breast-conserving surgery. Accurate lesion localization is therefore important. The current standard is wire-guided localization and although effective it involves a risk of high rates of positive margin and re-operations. New methods are emerging and radioactive seed localization (RSL) seems promising with regards to re-operation rates and logistics. In RSL a small titanium seed containing radioactive iodine is used to mark the lesion.
丹麦国家乳腺钼靶筛查计划使得更多不可触及的小乳腺肿瘤得以确诊，这些肿瘤适合进行保乳手术。因此，准确的病变定位至关重要。目前的标准是钢丝引导定位，尽管有效，但存在切缘阳性率高和再次手术的风险。新方法不断涌现，放射性种子定位（RSL）在再次手术率和后勤保障方面似乎很有前景。在RSL中，一个含有放射性碘的小钛种子被用于标记病变。
