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[腹腔镜根治性膀胱切除术。膀胱癌的新金标准?]

[Laparoscopic radical cystectomy. The new gold standard for bladder carcinoma?].

作者信息

Castillo Octavio A, Vitagliano Gonzalo, Vidal-Mora Ivar

机构信息

Facultad de Ciencias de la Salud, Unidad de Urología Clínica Indisa, Escuela de Medicina, Universidad Andrés Bello, Santiago, Chile.

出版信息

Arch Esp Urol. 2009 Nov;62(9):737-44. doi: 10.4321/s0004-06142009000900009.

Abstract

SUMMARY OBJECTIVES

The experience of a renowned Latin American laparoscopic center is reported and the differences with the open technique are thoroughly discussed.

METHODS

During a 7 year period a total of 85 laparoscopic cystectomies were performed; in 92%of the cases urinary diversion was performed extracorporeally. This accounted for: 14 anterior exanterations, 50 radical cystoprostatectomies, 7 radical cystectomies and 14 simple cystectomies. Male to female ratio was 3:1. Mean patient age was 63 years (range 29 to 83). Mean Body Mass Index (BMI) was 28 kg/m2(range 20 to 47). Operative data and long term results are analyzed.

RESULTS

All 85 procedures were completed laparoscopically without need for conversion to open surgery. Orthotopic neobladder, Santiago pouch, Studer, Fontana and Le Bag were performed in 42, 13, 16, 12 and 1 case respectively. Ileal conduit, Indiana pouch and Mainz II were employed in 24, 10 and 9 cases respectively. All Mainz II were performed intracorporeally. Mean operative time and blood loss were 279 minutes (range 180 to 375) and 436 ml (range 50 to 1.500) respectively. A total of 8 patients (11%) presented perioperative complications: 5 vascular lesions, 2 eviscerations and 2 septicemias. Delayed complications were observed in 7 cases (9%); 3 urinary sepsis, 1 ureteral stenosis, 2 spontaneous ruptures and 1 mesenteric ischemia. Mean hospital stay was 8.8 days (range de 4 to 28). There was no operative mortality. Mean follow-up was 18 months (range 2 to 68 months). Ten patients (13%) presented disease progression and death.

CONCLUSIONS

Laparoscopic radical cystectomy is associated with diminished operative bleeding, time to oral intake and hospital stay. Though this is a reproducible technique it demands a very long learning curve.

摘要

摘要目的

报告一家著名的拉丁美洲腹腔镜中心的经验,并深入讨论与开放手术技术的差异。

方法

在7年期间,共进行了85例腹腔镜膀胱切除术;92%的病例采用体外尿流改道术。其中包括:14例前盆腔清扫术、50例根治性膀胱前列腺切除术、7例根治性膀胱切除术和14例单纯膀胱切除术。男女比例为3:1。患者平均年龄为63岁(范围29至83岁)。平均体重指数(BMI)为28kg/m²(范围20至47)。分析手术数据和长期结果。

结果

所有85例手术均通过腹腔镜完成,无需转为开放手术。分别有42例、13例、16例、12例和1例患者接受了原位新膀胱、圣地亚哥囊袋、施图德、丰塔纳和勒袋手术。分别有24例、10例和9例患者采用了回肠导管、印第安纳囊袋和迈因茨II式手术。所有迈因茨II式手术均在体内完成。平均手术时间和失血量分别为279分钟(范围180至375分钟)和436毫升(范围50至1500毫升)。共有8例患者(11%)出现围手术期并发症:5例血管病变、2例脏器脱出和2例败血症。7例患者(9%)出现延迟并发症:3例尿脓毒症、1例输尿管狭窄、2例自发性破裂和1例肠系膜缺血。平均住院时间为8.8天(范围4至28天)。无手术死亡病例。平均随访时间为18个月(范围2至68个月)。10例患者(13%)出现疾病进展和死亡。

结论

腹腔镜根治性膀胱切除术可减少手术出血、缩短经口进食时间和住院时间。虽然这是一种可重复的技术,但需要很长的学习曲线。

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