Yu Zhaojun, Huang Jianbiao, Deng Huanhuan, Zeng Zhihua, Deng Leihong, Xu Xiangda, Chao Haichao, Zeng Tao
Department of Urology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, People's Republic of China.
Department of Urology, The People's Hospital Affiliated to Nanchang University, Nanchang, 330006, People's Republic of China.
Cancer Manag Res. 2021 Mar 30;13:2909-2915. doi: 10.2147/CMAR.S288673. eCollection 2021.
To explore the application of the neobladder-urethral drag-and-bond anastomosis technique in laparoscopic radical cystectomy (LRC) with ileal orthotopic neobladder (IONB) reconstruction.
This is a retrospective cohort study on a procedure performed by a single surgeon. From January 2014 to December 2018, we identified 43 male bladder cancer patients who received LRC with IONB reconstruction. These patients were divided into two groups, with 22 patients undergoing neobladder-urethral drag-and-bond anastomosis (NUDA) and 21 patients undergoing neobladder-urethral anastomosis under laparoscopy (NUAL). Anastomosis time, catheter removal time, postvoid residual (PVR), maximum urinary flow rate (Q-max), urine leakage and anastomotic stenosis were used to evaluate the simplicity and surgical effect of the two groups.
Both groups demonstrated similar tumor characteristics. A significant difference in neobladder-urethral anastomosis time was found between the NUDA group and the NUAL group (14.6 ± 0.4 vs 70 ± 2.5 min, P<0.0001), and there was no significant difference in other characteristics.
The neobladder-urethral drag-and-bond anastomosis technique in LRC and IONB reconstruction, with its shorter learning curve, was easier and more convenient than neobladder-urethral anastomosis under laparoscopy.
探讨新膀胱-尿道牵拉缝合吻合技术在腹腔镜根治性膀胱切除术(LRC)联合回肠原位新膀胱(IONB)重建术中的应用。
这是一项对单一外科医生所实施手术的回顾性队列研究。2014年1月至2018年12月,我们纳入了43例行LRC联合IONB重建术的男性膀胱癌患者。这些患者被分为两组,22例行新膀胱-尿道牵拉缝合吻合术(NUDA),21例行腹腔镜下新膀胱-尿道吻合术(NUAL)。采用吻合时间、拔管时间、残余尿量(PVR)、最大尿流率(Q-max)、尿漏及吻合口狭窄情况来评估两组手术的简便性及手术效果。
两组患者的肿瘤特征相似。NUDA组与NUAL组在新膀胱-尿道吻合时间上存在显著差异(14.6±0.4 vs 70±2.5分钟,P<0.0001),其他特征方面无显著差异。
在LRC联合IONB重建术中,新膀胱-尿道牵拉缝合吻合技术学习曲线较短,相较于腹腔镜下新膀胱-尿道吻合术更简便易行。