Woodson Erika A, Reiss Lina A J, Turner Christopher W, Gfeller Kate, Gantz Bruce J
Adv Otorhinolaryngol. 2010;67:125-134. doi: 10.1159/000262604. Epub 2009 Nov 25.
The Hybrid S or 'short-electrode' cochlear implant was developed to treat patients with a severe to profound hearing loss limited to the high frequencies. The short electrode is implanted into just the base or high-frequency region of the cochlea, with the goal of preserving residual low-frequency hearing. As a result, electric stimulation can be combined with acoustic stimulation in the same ear (and the opposite ear); this is one instance of 'acoustic plus electric' (A + E) stimulation. In this paper, we will review the latest findings from the first two stages of the clinical trial for the Hybrid concept in the United States. Generally, we will review surgical techniques, clinical trial criteria, residual hearing preservation, improvements in speech perception in quiet, and predictive factors for patient benefit. We will also discuss the significant benefit of A + E stimulation for speech perception in noise and musical measures of melody and instrument recognition, as well as valuable insights into central auditory nervous system plasticity gained from the use of a very short electrode array.
混合S型或“短电极”人工耳蜗是为治疗仅高频部分有重度至极重度听力损失的患者而研发的。短电极仅植入耳蜗的底部或高频区域,目的是保留残余的低频听力。因此,电刺激可与同一耳(及对侧耳)的声刺激相结合;这是“声加电”(A + E)刺激的一个实例。在本文中,我们将回顾美国针对混合概念进行的临床试验前两个阶段的最新研究结果。总体而言,我们将回顾手术技术、临床试验标准、残余听力保留情况、安静环境下言语感知的改善以及患者受益的预测因素。我们还将讨论A + E刺激对噪声环境下言语感知以及旋律和乐器识别的音乐测评的显著益处,以及使用非常短的电极阵列对中枢听觉神经系统可塑性的宝贵见解。