以色列北非第一代和第二代妇女宫颈癌的发病率。
Incidence rates of cervical carcinoma among first- and second-generation women of North African origin in Israel.
机构信息
Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel.
出版信息
Int J Gynecol Cancer. 2009 Dec;19(9):1606-9. doi: 10.1111/IGC.0b013e3181a84035.
OBJECTIVES
To evaluate the incidence rates of cervical cancer by ethnic origins and compare these rates between first- and second-generation women of North African origin.
METHODS
Data of all cervical carcinoma of Jewish women during 2000 to 2005 were obtained from the National Cancer Registry. Standardized incidence ratios for each ethnic origin category were calculated and compared using Poisson regression.
RESULTS
During the study period, 938 patients were examined. The standardized incidence ratios of North African-born women and of Israeli-born women of North African descent were significantly higher compared with those of women of other origins.
CONCLUSIONS
The persistence of a higher risk of cervical cancer in Israeli Jewish women of North African descent compared with those of other origins may suggest that genetic factors are involved in the etiology of this neoplasm.
目的
评估不同族裔人群的宫颈癌发病率，并比较北非裔第一代和第二代女性之间的发病率。
方法
本研究数据来源于 2000 年至 2005 年期间所有的犹太裔宫颈癌患者。使用泊松回归计算并比较各民族类别标准化发病率比值。
结果
研究期间共检查了 938 例患者。与其他族裔的女性相比，北非出生的女性和以色列出生的北非裔女性的标准化发病率比值显著更高。
结论
与其他族裔的女性相比，以色列犹太裔北非裔女性宫颈癌发病风险更高，这可能提示遗传因素在这种肿瘤的发病机制中起作用。
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