Department of Pathology, Instituto Nacional de Rehabilitación, Mexico City, México.
J Clin Rheumatol. 2009 Dec;15(8):393-5. doi: 10.1097/RHU.0b013e3181c3f894.
Pigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovial membrane of uncertain etiology. It commonly affects synovial joints of the appendicular skeleton and rarely affects the spine. We present the case of a young man presenting with a rapidly progressive myelopathy due to spinal cord compression by PVNS arising from a thoracic facet joint, which finally resulted in paraplegia.The spinal location of PVNS has been seldom emphasized in the rheumatologic literature. PVNS should be considered as a possible cause of soft tissue masses arising from the facet joints, with variable degrees of nerve root or spinal cord compression.
色素沉着绒毛结节性滑膜炎 (PVNS) 是一种滑膜膜的增生性疾病,病因不明。它通常影响四肢骨骼的滑膜关节,很少影响脊柱。我们报告了一例年轻人的病例,由于源自胸椎间关节的 PVNS 引起的脊髓压迫导致进行性加重的脊髓病,最终导致截瘫。PVNS 的脊柱位置在风湿病学文献中很少被强调。PVNS 应该被认为是来自小关节的软组织肿块的可能原因,其具有不同程度的神经根或脊髓压迫。