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Predictive Factors for Response and Toxicity in Chemotherapy: Pharmacogenomics.

作者信息

Sanoff Hanna K, McLeod Howard L

机构信息

Department of Medicine, Division of Hematology Oncology, University of North Carolina, Chapel Hill, NC, USA.

出版信息

Semin Colon Rectal Surg. 2008 Dec;19(4):226-230. doi: 10.1053/j.scrs.2008.09.007.

DOI:10.1053/j.scrs.2008.09.007
PMID:19956343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2614280/
Abstract
摘要

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本文引用的文献

1
Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial.FOLFOX4围手术期化疗联合手术与单纯手术治疗可切除的结直肠癌肝转移（欧洲癌症研究与治疗组织（EORTC）国际协作组试验40983）：一项随机对照试验
Lancet. 2008 Mar 22;371(9617):1007-16. doi: 10.1016/S0140-6736(08)60455-9.
2
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study.伊立替康联合持续静脉输注、大剂量推注或口服氟嘧啶用于转移性结直肠癌一线治疗的随机对照试验：BICC-C研究结果
J Clin Oncol. 2007 Oct 20;25(30):4779-86. doi: 10.1200/JCO.2007.11.3357.
3
UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters.UGT1A1*28基因分型与伊立替康诱导的中性粒细胞减少：剂量至关重要。
J Natl Cancer Inst. 2007 Sep 5;99(17):1290-5. doi: 10.1093/jnci/djm115. Epub 2007 Aug 28.
4
Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803.伊立替康联合氟尿嘧啶及亚叶酸钙作为Ⅲ期结肠癌辅助治疗并不优于单独使用氟尿嘧啶及亚叶酸钙：癌症和白血病B组89803研究结果
J Clin Oncol. 2007 Aug 10;25(23):3456-61. doi: 10.1200/JCO.2007.11.2144.
5
Should DPD analysis be required prior to prescribing fluoropyrimidines?在开具氟嘧啶类药物之前是否需要进行二氢嘧啶脱氢酶（DPD）分析？
Eur J Cancer. 2007 Apr;43(6):1011-6. doi: 10.1016/j.ejca.2007.01.030. Epub 2007 Mar 12.
6
Dihydropyrimidine dehydrogenase activity and the IVS14+1G>A mutation in patients developing 5FU-related toxicity.发生5-氟尿嘧啶相关毒性的患者的二氢嘧啶脱氢酶活性及IVS14+1G>A突变
Br J Clin Pharmacol. 2007 Aug;64(2):237-40. doi: 10.1111/j.1365-2125.2007.02869.x. Epub 2007 Mar 1.
7
Methylation of the DPYD promoter: an alternative mechanism for dihydropyrimidine dehydrogenase deficiency in cancer patients.DPYD启动子的甲基化：癌症患者二氢嘧啶脱氢酶缺乏的一种替代机制。
Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8699-705. doi: 10.1158/1078-0432.CCR-05-1520.
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Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: a molecular and clinical study of 75 patients.不同UGT1A1基因多态性与伊立替康所致毒性的相关性：75例患者的分子与临床研究
Clin Cancer Res. 2004 Aug 1;10(15):5151-9. doi: 10.1158/1078-0432.CCR-03-0548.
9
UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer.转移性结直肠癌患者的UGT1A1基因变异与伊立替康治疗
Br J Cancer. 2004 Aug 16;91(4):678-82. doi: 10.1038/sj.bjc.6602042.
10
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.奥沙利铂、氟尿嘧啶和亚叶酸作为结肠癌的辅助治疗。
N Engl J Med. 2004 Jun 3;350(23):2343-51. doi: 10.1056/NEJMoa032709.