Haider Waseem, Munroe Norman, Pulletikurthi Chandan, Singh Gill Puneet K, Amruthaluri Sushma
Applied Research Center, Florida International University, 10555 West Flagler Street, Miami, FL 33174.
J Mater Eng Perform. 2009 Aug 1;18(5-6):760-764. doi: 10.1007/s11665-009-9435-5.
Nitinol alloys are rapidly being utilized as the material of choice in a variety of applications in the medical industry. It has been used for self-expanding stents, graft support systems, and various other devices for minimally invasive interventional and endoscopic procedures. However, the biocompatibility of this alloy remains a concern to many practitioners in the industry due to nickel sensitivity experienced by many patients. In recent times, several new Nitinol alloys have been introduced with the addition of a ternary element. Nevertheless, there is still a dearth of information concerning the biocompatibility and corrosion resistance of these alloys. This study compared the biocompatibility of two ternary Nitinol alloys prepared by powder metallurgy (PM) and arc melting (AM) and critically assessed the influence of the ternary element. ASTM F 2129-08 cyclic polarization in vitro corrosion tests were conducted to evaluate the corrosion resistance in phosphate buffered saline (PBS). The growth of endothelial cells on NiTi was examined using optical microscopy.
镍钛诺合金正迅速成为医疗行业各种应用中的首选材料。它已被用于自膨胀支架、移植支撑系统以及用于微创介入和内窥镜手术的各种其他设备。然而，由于许多患者对镍敏感，这种合金的生物相容性仍然是该行业许多从业者关注的问题。近年来，随着三元元素的加入，几种新型镍钛诺合金被推出。然而，关于这些合金的生物相容性和耐腐蚀性的信息仍然匮乏。本研究比较了通过粉末冶金（PM）和电弧熔炼（AM）制备的两种三元镍钛诺合金的生物相容性，并严格评估了三元元素的影响。进行了ASTM F 2129 - 08体外循环极化腐蚀试验，以评估在磷酸盐缓冲盐水（PBS）中的耐腐蚀性。使用光学显微镜检查内皮细胞在镍钛合金上的生长情况。
