[四川省喜马拉雅旱獭鼠疫自然疫源地研究]

[Study on the natural foci of Marmota himalayana plague in Sichuan province].

作者信息

Wang Li-Mao, Luo Zhi-Danba, Yue Qi, Duan Yong-Jun, Zhu Xiao-Ping, Mao Su-Ling, Liu Lun-Guang, Wang Hong, Liu Yi, Xie Fei, Chen De-Gang, Chen Kai-Hua, Deng Bing, Kang Jun-Xing

机构信息

Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Jun;30(6):601-5.

PMID:19957628

Abstract

OBJECTIVE

To explore the existence of natural foci on Marmota himalayana plague in Sichuan province and to provide basis for prevention and control of the disease.

METHODS

Both epidemiological investigation and laboratory tests were used to provide the host animal and fleas of the vectors with Yersinia pestis carriers.

RESULTS

30 species of animals were found to belong to 10 orders. Ochotona curzoniae and M. himalayana were the most common ones while 7 species of the fleas belonged to 7 genera and 3 families. M. himalayana was the main reservoirs while Callopsylla dolabris and Oropsylla silantiewi served as vectors. The 13 Y. pestis were identified from 43 Marmota samples. 8 samples were identified under IHA, with the highest titer of herding-dogs serum as 1:10,240. 19 samples were F1 antigen positive using RIHA and the highest titer of M. himalayana serum was 1:409,600. The major foci was 4545 km2, distributed at Dege county in Sichuan province.

CONCLUSION

We have confirmed the existence of natural foci on M. himalayana plague in Sichuan province.

摘要

目的

探讨四川省喜马拉雅旱獭鼠疫自然疫源地的存在情况，为该病的防控提供依据。

方法

采用流行病学调查和实验室检测相结合的方法，查找鼠疫耶尔森菌携带者的宿主动物和媒介蚤类。

结果

共发现10目30种动物，其中藏鼠兔和喜马拉雅旱獭最为常见；发现蚤类7种，分属3科7属。喜马拉雅旱獭为主要宿主，斧形盖蚤和谢氏山蚤为主要媒介。从43份喜马拉雅旱獭样本中检出13株鼠疫菌。间接血凝试验（IHA）检测8份样本呈阳性，其中牧犬血清最高效价为1:10240；反向间接血凝试验（RIHA）检测19份样本F1抗原呈阳性，其中喜马拉雅旱獭血清最高效价为1: 409600。主要疫源地面积为4545平方公里，分布于四川省德格县。