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[将脂联素用作心血管疾病生物标志物的预后、诊断及治疗前景]

[Prognostic, diagnostic, and therapeutic prospects of using adiponectine as a biomarker in cardiobascular diseases].

作者信息

Pal'tseva E M, Rodina A V, Konstantinova S V, Ermakov N V, Andreev D A, Syrkin A L, Severin S E

出版信息

Ross Fiziol Zh Im I M Sechenova. 2009 Oct;95(10):1024-40.

Abstract

The role of adipose tissue as an important endocrine organ is today beyond doubt. The adipose tissue is known to be a source of many biologically active substances, adipocitokines, one of them being the adiponectine possessing anti-inflammatory, antiatherogenic and cardioprotective properties; it is believed to be one of prospective biomarkers for risk assessment, for diagnostics and, possibly, for therapy of cardiovascular diseases.

摘要

如今,脂肪组织作为一个重要内分泌器官的作用毋庸置疑。众所周知,脂肪组织是许多生物活性物质即脂肪细胞因子的来源,其中之一是具有抗炎、抗动脉粥样硬化和心脏保护特性的脂联素;它被认为是用于风险评估、诊断以及可能用于心血管疾病治疗的潜在生物标志物之一。

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