An update of mortality due to brain neoplasms and other causes among employees of a petrochemical facility.

In an update of an earlier investigation of brain tumors, mortality patterns were examined for 7849 male employees who worked at a petrochemical plant from 1941 through 1983. The update added 6 years of observation (1978 to 1983). During this period, the brain tumor (BT) mortality risk declined relative to the US population, but continued to be higher than expected in hourly workers (5 observed/3.4 expected). Similar to the earlier studies, BT occurrence was not explained by patterns of production work assignments. Mortality rates for hourly and salaried workers from all causes combined, total cancer and respiratory cancer were lower than US population rates. Lower rates for these causes were also seen for white and nonwhite production and maintenance workers. Liver cancer rates were greater than expected in white production workers (3 observed/1.6 expected) and included two men assigned more than 40 years ago to vinyl chloride-related departments. Mortality rates due to malignant melanoma were elevated in white maintenance workers (5 observed/2.0 expected) and may be explained by heavy sun exposure in outdoor work.