Department of Dermatology, Churchill Hospital, Oxford, UK.
Clin Exp Dermatol. 2010 Jun;35(4):e130-2. doi: 10.1111/j.1365-2230.2009.03751.x. Epub 2009 Dec 2.
We describe a patient with previous solid-organ (testicular, oesophageal) and haematological (acute myeloid leukaemia) malignancies, in whom chronic cutaneous graft-versus-host disease was complicated by poromas and porokeratosis. Chemotherapy, total body irradiation, longstanding immunosuppression and ultraviolet radiation may all have played a part in the pathogenesis of the skin tumours.
我们描述了一名患有既往实体器官(睾丸、食管)和血液系统(急性髓系白血病)恶性肿瘤的患者,其慢性皮肤移植物抗宿主病并发了汗孔瘤和角化棘皮瘤。化疗、全身照射、长期免疫抑制和紫外线辐射都可能在皮肤肿瘤的发病机制中发挥了作用。